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A human mitofusin 2 mutation can cause mitophagic cardiomyopathy.
Franco A, Li J, Kelly DP, Hershberger RE, Marian AJ, Lewis RM, Song M, Dang X, Schmidt AD, Mathyer ME, Edwards JR, Strong CG, Dorn GW. Franco A, et al. Elife. 2023 Nov 1;12:e84235. doi: 10.7554/eLife.84235. Elife. 2023. PMID: 37910431 Free PMC article.
Two-hit mouse model of heart failure with preserved ejection fraction combining diet-induced obesity and renin-mediated hypertension.
Berger JH, Shi Y, Matsuura TR, Batmanov K, Chen X, Tam K, Marshall M, Kue R, Patel J, Taing R, Callaway R, Griffin J, Kovacs A, Hirenallur-Shanthappa D, Miller R, Zhang BB, Flach RJR, Kelly DP. Berger JH, et al. Sci Rep. 2025 Jan 2;15(1):422. doi: 10.1038/s41598-024-84515-9. Sci Rep. 2025. PMID: 39747575 Free PMC article.