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Page 1
Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes.
Feyen DAM, McKeithan WL, Bruyneel AAN, Spiering S, Hörmann L, Ulmer B, Zhang H, Briganti F, Schweizer M, Hegyi B, Liao Z, Pölönen RP, Ginsburg KS, Lam CK, Serrano R, Wahlquist C, Kreymerman A, Vu M, Amatya PL, Behrens CS, Ranjbarvaziri S, Maas RGC, Greenhaw M, Bernstein D, Wu JC, Bers DM, Eschenhagen T, Metallo CM, Mercola M. Feyen DAM, et al. Cell Rep. 2020 Jul 21;32(3):107925. doi: 10.1016/j.celrep.2020.107925. Cell Rep. 2020. PMID: 32697997 Free PMC article.
Human iPSC modeling of heart disease for drug development.
Hnatiuk AP, Briganti F, Staudt DW, Mercola M. Hnatiuk AP, et al. Cell Chem Biol. 2021 Mar 18;28(3):271-282. doi: 10.1016/j.chembiol.2021.02.016. Cell Chem Biol. 2021. PMID: 33740432 Free PMC article. Review.
A deep learning platform to assess drug proarrhythmia risk.
Serrano R, Feyen DAM, Bruyneel AAN, Hnatiuk AP, Vu MM, Amatya PL, Perea-Gil I, Prado M, Seeger T, Wu JC, Karakikes I, Mercola M. Serrano R, et al. Cell Stem Cell. 2023 Jan 5;30(1):86-95.e4. doi: 10.1016/j.stem.2022.12.002. Epub 2022 Dec 22. Cell Stem Cell. 2023. PMID: 36563695 Free PMC article.
Identification of a dihydropyridine scaffold that blocks ryanodine receptors.
Gunaratne GS, Rebbeck RT, McGurran LM, Yan Y, Arzua T, Frolkis T, Sprague DJ, Bai X, Cornea RL, Walseth TF, Marchant JS. Gunaratne GS, et al. iScience. 2021 Dec 27;25(1):103706. doi: 10.1016/j.isci.2021.103706. eCollection 2022 Jan 21. iScience. 2021. PMID: 35059610 Free PMC article.
Synergistic FRET assays for drug discovery targeting RyR2 channels.
Rebbeck R, Ginsburg KS, Ko CY, Fasoli A, Rusch K, Cai GF, Dong X, Thomas DD, Bers DM, Cornea RL. Rebbeck R, et al. J Mol Cell Cardiol. 2022 Jul;168:13-23. doi: 10.1016/j.yjmcc.2022.04.002. Epub 2022 Apr 9. J Mol Cell Cardiol. 2022. PMID: 35405106 Free PMC article.
44 results