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Page 1
Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis.
Gaul S, Leszczynska A, Alegre F, Kaufmann B, Johnson CD, Adams LA, Wree A, Damm G, Seehofer D, Calvente CJ, Povero D, Kisseleva T, Eguchi A, McGeough MD, Hoffman HM, Pelegrin P, Laufs U, Feldstein AE. Gaul S, et al. J Hepatol. 2021 Jan;74(1):156-167. doi: 10.1016/j.jhep.2020.07.041. Epub 2020 Aug 4. J Hepatol. 2021. PMID: 32763266 Free PMC article.
CAPS and NLRP3.
Booshehri LM, Hoffman HM. Booshehri LM, et al. J Clin Immunol. 2019 Apr;39(3):277-286. doi: 10.1007/s10875-019-00638-z. Epub 2019 May 10. J Clin Immunol. 2019. PMID: 31077002 Free PMC article. Review.
Interleukin-18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis.
Knorr J, Kaufmann B, Inzaugarat ME, Holtmann TM, Geisler L, Hundertmark J, Kohlhepp MS, Boosheri LM, Chilin-Fuentes DR, Birmingham A, Fisch KM, Schilling JD, Loosen SH, Trautwein C, Roderburg C, Demir M, Tacke F, Hoffman HM, Feldstein AE, Wree A. Knorr J, et al. Hepatology. 2023 Jun 1;77(6):1968-1982. doi: 10.1002/hep.32776. Epub 2022 Oct 12. Hepatology. 2023. PMID: 36059147 Free PMC article.
Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 Production.
Sanchez-Lopez E, Zhong Z, Stubelius A, Sweeney SR, Booshehri LM, Antonucci L, Liu-Bryan R, Lodi A, Terkeltaub R, Lacal JC, Murphy AN, Hoffman HM, Tiziani S, Guma M, Karin M. Sanchez-Lopez E, et al. Cell Metab. 2019 Jun 4;29(6):1350-1362.e7. doi: 10.1016/j.cmet.2019.03.011. Epub 2019 Apr 11. Cell Metab. 2019. PMID: 30982734 Free PMC article.
JAK inhibitors in autoinflammation.
Hoffman HM, Broderick L. Hoffman HM, et al. J Clin Invest. 2018 Jul 2;128(7):2760-2762. doi: 10.1172/JCI121526. Epub 2018 Jun 11. J Clin Invest. 2018. PMID: 29889100 Free PMC article.
The human milk oligosaccharide 3'sialyllactose reduces low-grade inflammation and atherosclerosis development in mice.
Pessentheiner AR, Spann NJ, Autran CA, Oh TG, Grunddal KV, Coker JK, Painter CD, Ramms B, Chiang AW, Wang CY, Hsiao J, Wang Y, Quach A, Booshehri LM, Hammond A, Tognaccini C, Latasiewicz J, Willemsen L, Zengler K, de Winther MP, Hoffman HM, Philpott M, Cribbs AP, Oppermann U, Lewis NE, Witztum JL, Yu R, Atkins AR, Downes M, Evans RM, Glass CK, Bode L, Gordts PL. Pessentheiner AR, et al. JCI Insight. 2024 Nov 8;9(21):e181329. doi: 10.1172/jci.insight.181329. JCI Insight. 2024. PMID: 39325548 Free PMC article.
38 results