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3D Imaging Reveals Complex Microvascular Remodeling in the Right Ventricle in Pulmonary Hypertension.
Ichimura K, Boehm M, Andruska AM, Zhang F, Schimmel K, Bonham S, Kabiri A, Kheyfets VO, Ichimura S, Reddy S, Mao Y, Zhang T, Wang GX, Santana EJ, Tian X, Essafri I, Vinh R, Tian W, Nicolls MR, Yajima S, Shudo Y, MacArthur JW, Woo YJ, Metzger RJ, Spiekerkoetter E. Ichimura K, et al. Circ Res. 2024 Jun 21;135(1):60-75. doi: 10.1161/CIRCRESAHA.123.323546. Epub 2024 May 21. Circ Res. 2024. PMID: 38770652
MicroRNA-34a-Dependent Attenuation of Angiogenesis in Right Ventricular Failure.
Reddy S, Hu DQ, Zhao M, Ichimura S, Barnes EA, Cornfield DN, Alejandre Alcázar MA, Spiekerkoetter E, Fajardo G, Bernstein D. Reddy S, et al. J Am Heart Assoc. 2024 Feb 6;13(3):e029427. doi: 10.1161/JAHA.123.029427. Epub 2024 Jan 31. J Am Heart Assoc. 2024. PMID: 38293915 Free PMC article.
Targeted proteomics of right heart adaptation to pulmonary arterial hypertension.
Amsallem M, Sweatt AJ, Arthur Ataam J, Guihaire J, Lecerf F, Lambert M, Ghigna MR, Ali MK, Mao Y, Fadel E, Rabinovitch M, de Jesus Perez V, Spiekerkoetter E, Mercier O, Haddad F, Zamanian RT. Amsallem M, et al. Eur Respir J. 2021 Apr 8;57(4):2002428. doi: 10.1183/13993003.02428-2020. Print 2021 Apr. Eur Respir J. 2021. PMID: 33334941 Free PMC article.
Novel left ventricular mechanical index in pulmonary arterial hypertension.
Ichimura K, Santana EJ, Kuznetsova T, Cauwenberghs N, Sabovčik F, Chun L, Francisco NLC, Kheyfets VO, Salerno M, Zamanian RT, Spiekerkoetter E, Haddad F. Ichimura K, et al. Pulm Circ. 2023 Apr 1;13(2):e12216. doi: 10.1002/pul2.12216. eCollection 2023 Apr. Pulm Circ. 2023. PMID: 37063750 Free PMC article.
Improving Right Ventricular Function by Increasing BMP Signaling with FK506.
Boehm M, Tian X, Ali MK, Mao Y, Ichimura K, Zhao M, Kuramoto K, Dannewitz Prosseda S, Fajardo G, Dufva MJ, Qin X, Kheyfets VO, Bernstein D, Reddy S, Metzger RJ, Zamanian RT, Haddad F, Spiekerkoetter E. Boehm M, et al. Am J Respir Cell Mol Biol. 2021 Sep;65(3):272-287. doi: 10.1165/rcmb.2020-0528OC. Am J Respir Cell Mol Biol. 2021. PMID: 33938785 Free PMC article.
Severe Pulmonary Arterial Hypertension Is Characterized by Increased Neutrophil Elastase and Relative Elafin Deficiency.
Sweatt AJ, Miyagawa K, Rhodes CJ, Taylor S, Del Rosario PA, Hsi A, Haddad F, Spiekerkoetter E, Bental-Roof M, Bland RD, Swietlik EM, Gräf S, Wilkins MR, Morrell NW, Nicolls MR, Rabinovitch M, Zamanian RT. Sweatt AJ, et al. Chest. 2021 Oct;160(4):1442-1458. doi: 10.1016/j.chest.2021.06.028. Epub 2021 Jun 26. Chest. 2021. PMID: 34181952 Free PMC article.