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Rigor and reproducibility in human brain organoid research: Where we are and where we need to go.
Sandoval SO, Cappuccio G, Kruth K, Osenberg S, Khalil SM, Méndez-Albelo NM, Padmanabhan K, Wang D, Niciu MJ, Bhattacharyya A, Stein JL, Sousa AMM, Waxman EA, Buttermore ED, Whye D, Sirois CL; Cross-IDDRC Human Stem Cell Consortium; Williams A, Maletic-Savatic M, Zhao X. Sandoval SO, et al. Stem Cell Reports. 2024 Jun 11;19(6):796-816. doi: 10.1016/j.stemcr.2024.04.008. Epub 2024 May 16. Stem Cell Reports. 2024. PMID: 38759644 Free PMC article. Review.
Cross-site reproducibility of human cortical organoids reveals consistent cell type composition and architecture.
Glass MR, Waxman EA, Yamashita S, Lafferty M, Beltran A, Farah T, Patel NK, Matoba N, Ahmed S, Srivastava M, Drake E, Davis LT, Yeturi M, Sun K, Love MI, Hashimoto-Torii K, French DL, Stein JL. Glass MR, et al. bioRxiv [Preprint]. 2023 Jul 29:2023.07.28.550873. doi: 10.1101/2023.07.28.550873. bioRxiv. 2023. Update in: Stem Cell Reports. 2024 Sep 10;19(9):1351-1367. doi: 10.1016/j.stemcr.2024.07.008 PMID: 37546772 Free PMC article. Updated. Preprint.
Segmentor: a tool for manual refinement of 3D microscopy annotations.
Borland D, McCormick CM, Patel NK, Krupa O, Mory JT, Beltran AA, Farah TM, Escobar-Tomlienovich CF, Olson SS, Kim M, Wu G, Stein JL. Borland D, et al. BMC Bioinformatics. 2021 May 22;22(1):260. doi: 10.1186/s12859-021-04202-8. BMC Bioinformatics. 2021. PMID: 34022787 Free PMC article.
Wnt activity reveals context-specific genetic effects on gene regulation in neural progenitors.
Matoba N, Le BD, Valone JM, Wolter JM, Mory J, Liang D, Aygün N, Broadaway KA, Bond ML, Mohlke KL, Zylka MJ, Love MI, Stein JL. Matoba N, et al. bioRxiv [Preprint]. 2023 Apr 19:2023.02.07.527357. doi: 10.1101/2023.02.07.527357. bioRxiv. 2023. Update in: Nat Neurosci. 2024 Dec;27(12):2430-2442. doi: 10.1038/s41593-024-01773-6 PMID: 36798360 Free PMC article. Updated. Preprint.
11 results