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Page 1
Small GTPase ARF6 controls VEGFR2 trafficking and signaling in diabetic retinopathy.
Zhu W, Shi DS, Winter JM, Rich BE, Tong Z, Sorensen LK, Zhao H, Huang Y, Tai Z, Mleynek TM, Yoo JH, Dunn C, Ling J, Bergquist JA, Richards JR, Jiang A, Lesniewski LA, Hartnett ME, Ward DM, Mueller AL, Ostanin K, Thomas KR, Odelberg SJ, Li DY. Zhu W, et al. J Clin Invest. 2017 Dec 1;127(12):4569-4582. doi: 10.1172/JCI91770. Epub 2017 Oct 23. J Clin Invest. 2017. PMID: 29058688 Free PMC article.
Lack of CCM1 induces hypersprouting and impairs response to flow.
Mleynek TM, Chan AC, Redd M, Gibson CC, Davis CT, Shi DS, Chen T, Carter KL, Ling J, Blanco R, Gerhardt H, Whitehead K, Li DY. Mleynek TM, et al. Hum Mol Genet. 2014 Dec 1;23(23):6223-34. doi: 10.1093/hmg/ddu342. Epub 2014 Jul 2. Hum Mol Genet. 2014. PMID: 24990152 Free PMC article.
ARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma.
Yoo JH, Shi DS, Grossmann AH, Sorensen LK, Tong Z, Mleynek TM, Rogers A, Zhu W, Richards JR, Winter JM, Zhu J, Dunn C, Bajji A, Shenderovich M, Mueller AL, Woodman SE, Harbour JW, Thomas KR, Odelberg SJ, Ostanin K, Li DY. Yoo JH, et al. Cancer Cell. 2016 Jun 13;29(6):889-904. doi: 10.1016/j.ccell.2016.04.015. Epub 2016 Jun 2. Cancer Cell. 2016. PMID: 27265506 Free PMC article.
Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation.
Gibson CC, Zhu W, Davis CT, Bowman-Kirigin JA, Chan AC, Ling J, Walker AE, Goitre L, Delle Monache S, Retta SF, Shiu YT, Grossmann AH, Thomas KR, Donato AJ, Lesniewski LA, Whitehead KJ, Li DY. Gibson CC, et al. Circulation. 2015 Jan 20;131(3):289-99. doi: 10.1161/CIRCULATIONAHA.114.010403. Epub 2014 Dec 8. Circulation. 2015. PMID: 25486933 Free PMC article.