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Page 1
Histidine-Covalent Stapled Alpha-Helical Peptides Targeting hMcl-1.
Alboreggia G, Udompholkul P, Baggio C, Muzzarelli K, Assar Z, Pellecchia M. Alboreggia G, et al. J Med Chem. 2024 May 23;67(10):8172-8185. doi: 10.1021/acs.jmedchem.4c00277. Epub 2024 May 2. J Med Chem. 2024. PMID: 38695666 Free PMC article.
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-7.
Gütschow M, Eynde JJV, Jampilek J, Kang C, Mangoni AA, Fossa P, Karaman R, Trabocchi A, Scott PJH, Reynisson J, Rapposelli S, Galdiero S, Winum JY, Brullo C, Prokai-Tatrai K, Sharma AK, Schapira M, Azuma YT, Cerchia L, Spetea M, Torri G, Collina S, Geronikaki A, García-Sosa AT, Vasconcelos MH, Sousa ME, Kosalec I, Tuccinardi T, Duarte IF, Salvador JAR, Bertinaria M, Pellecchia M, Amato J, Rastelli G, Gomes PAC, Guedes RC, Sabatier JM, Estévez-Braun A, Pagano B, Mangani S, Ragno R, Kokotos G, Brindisi M, González FV, Borges F, Miloso M, Rautio J, Muñoz-Torrero D. Gütschow M, et al. Molecules. 2020 Jun 28;25(13):2968. doi: 10.3390/molecules25132968. Molecules. 2020. PMID: 32605268 Free PMC article.
Targeted degradation of Pin1 by protein-destabilizing compounds.
Alboreggia G, Udompholkul P, Rodriguez I, Blaha G, Pellecchia M. Alboreggia G, et al. Proc Natl Acad Sci U S A. 2024 Nov 19;121(47):e2403330121. doi: 10.1073/pnas.2403330121. Epub 2024 Nov 12. Proc Natl Acad Sci U S A. 2024. PMID: 39531501 Free PMC article.
NMR-Guided Design of Potent and Selective EphA4 Agonistic Ligands.
Baggio C, Kulinich A, Dennys CN, Rodrigo R, Meyer K, Ethell I, Pellecchia M. Baggio C, et al. J Med Chem. 2021 Aug 12;64(15):11229-11246. doi: 10.1021/acs.jmedchem.1c00608. Epub 2021 Jul 22. J Med Chem. 2021. PMID: 34293864 Free PMC article.
Constrained β-Hairpins Targeting the EphA4 Ligand Binding Domain.
Prentiss AM, Baggio C, Pagett J, Kulinich AO, Ethell IM, Muzzarelli K, Assar Z, Pellecchia M. Prentiss AM, et al. J Med Chem. 2024 Dec 26;67(24):22245-22253. doi: 10.1021/acs.jmedchem.4c02286. Epub 2024 Dec 10. J Med Chem. 2024. PMID: 39656022 Free PMC article.
21 results