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Thalamocortical organoids enable in vitro modeling of 22q11.2 microdeletion associated with neuropsychiatric disorders.
Shin D, Kim CN, Ross J, Hennick KM, Wu SR, Paranjape N, Leonard R, Wang JC, Keefe MG, Pavlovic BJ, Donohue KC, Moreau C, Wigdor EM, Larson HH, Allen DE, Cadwell CR, Bhaduri A, Popova G, Bearden CE, Pollen AA, Jacquemont S, Sanders SJ, Haussler D, Wiita AP, Frost NA, Sohal VS, Nowakowski TJ. Shin D, et al. Cell Stem Cell. 2024 Mar 7;31(3):421-432.e8. doi: 10.1016/j.stem.2024.01.010. Epub 2024 Feb 20. Cell Stem Cell. 2024. PMID: 38382530
Tropism of SARS-CoV-2 for human cortical astrocytes.
Andrews MG, Mukhtar T, Eze UC, Simoneau CR, Ross J, Parikshak N, Wang S, Zhou L, Koontz M, Velmeshev D, Siebert CV, Gemenes KM, Tabata T, Perez Y, Wang L, Mostajo-Radji MA, de Majo M, Donohue KC, Shin D, Salma J, Pollen AA, Nowakowski TJ, Ullian E, Kumar GR, Winkler EA, Crouch EE, Ott M, Kriegstein AR. Andrews MG, et al. Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2122236119. doi: 10.1073/pnas.2122236119. Epub 2022 Jul 12. Proc Natl Acad Sci U S A. 2022. PMID: 35858406 Free PMC article.
Ciliary biology intersects autism and congenital heart disease.
Teerikorpi N, Lasser MC, Wang S, Kostyanovskaya E, Bader E, Sun N, Dea J, Nowakowski TJ, Willsey AJ, Willsey HR. Teerikorpi N, et al. bioRxiv [Preprint]. 2024 Jul 31:2024.07.30.602578. doi: 10.1101/2024.07.30.602578. bioRxiv. 2024. PMID: 39131273 Free PMC article. Preprint.
Massively parallel characterization of psychiatric disorder-associated and cell-type-specific regulatory elements in the developing human cortex.
Deng C, Whalen S, Steyert M, Ziffra R, Przytycki PF, Inoue F, Pereira DA, Capauto D, Norton S, Vaccarino FM, Pollen A, Nowakowski TJ, Ahituv N, Pollard KS. Deng C, et al. bioRxiv [Preprint]. 2023 Feb 16:2023.02.15.528663. doi: 10.1101/2023.02.15.528663. bioRxiv. 2023. Update in: Science. 2024 May 24;384(6698):eadh0559. doi: 10.1126/science.adh0559 PMID: 36824845 Free PMC article. Updated. Preprint.
Pathological microcircuits initiate epileptiform events in patient hippocampal slices.
Elliott MAT, Andrews JP, van der Molen T, Geng J, Spaeth A, Voituik K, Core C, Gillespie T, Sinervo A, Parks DF, Robbins A, Solís D, Chang EF, Nowakowski TJ, Teodorescu M, Haussler D, Sharf T. Elliott MAT, et al. bioRxiv [Preprint]. 2024 Nov 14:2024.11.13.623525. doi: 10.1101/2024.11.13.623525. bioRxiv. 2024. PMID: 39605666 Free PMC article. Preprint.