R01-CA112399/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

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2006	1
2010	2
2025	0

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Deficiency of the transcriptional regulator p8 results in increased autophagy and apoptosis, and causes impaired heart function.

Kong DK, Georgescu SP, Cano C, Aronovitz MJ, Iovanna JL, Patten RD, Kyriakis JM, Goruppi S. Kong DK, et al. Mol Biol Cell. 2010 Apr 15;21(8):1335-49. doi: 10.1091/mbc.e09-09-0818. Epub 2010 Feb 24. Mol Biol Cell. 2010. PMID: 20181828 Free PMC article.

Mixed-lineage kinase 3 regulates B-Raf through maintenance of the B-Raf/Raf-1 complex and inhibition by the NF2 tumor suppressor protein.

Chadee DN, Xu D, Hung G, Andalibi A, Lim DJ, Luo Z, Gutmann DH, Kyriakis JM. Chadee DN, et al. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4463-8. doi: 10.1073/pnas.0510651103. Epub 2006 Mar 13. Proc Natl Acad Sci U S A. 2006. PMID: 16537381 Free PMC article.

Mammalian Ste20-like kinase (Mst2) indirectly supports Raf-1/ERK pathway activity via maintenance of protein phosphatase-2A catalytic subunit levels and consequent suppression of inhibitory Raf-1 phosphorylation.

Kilili GK, Kyriakis JM. Kilili GK, et al. J Biol Chem. 2010 May 14;285(20):15076-15087. doi: 10.1074/jbc.M109.078915. Epub 2010 Mar 8. J Biol Chem. 2010. PMID: 20212043 Free PMC article.

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