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Page 1
Pancreatic cancer: Advances and challenges.
Halbrook CJ, Lyssiotis CA, Pasca di Magliano M, Maitra A. Halbrook CJ, et al. Cell. 2023 Apr 13;186(8):1729-1754. doi: 10.1016/j.cell.2023.02.014. Cell. 2023. PMID: 37059070 Free PMC article. Review.
Analysis of Donor Pancreata Defines the Transcriptomic Signature and Microenvironment of Early Neoplastic Lesions.
Carpenter ES, Elhossiny AM, Kadiyala P, Li J, McGue J, Griffith BD, Zhang Y, Edwards J, Nelson S, Lima F, Donahue KL, Du W, Bischoff AC, Alomari D, Watkoske HR, Mattea M, The S, Espinoza CE, Barrett M, Sonnenday CJ, Olden N, Chen CT, Peterson N, Gunchick V, Sahai V, Rao A, Bednar F, Shi J, Frankel TL, Pasca di Magliano M. Carpenter ES, et al. Cancer Discov. 2023 Jun 2;13(6):1324-1345. doi: 10.1158/2159-8290.CD-23-0013. Cancer Discov. 2023. PMID: 37021392 Free PMC article.
Oncogenic KRAS-Dependent Stromal Interleukin-33 Directs the Pancreatic Microenvironment to Promote Tumor Growth.
Donahue KL, Watkoske HR, Kadiyala P, Du W, Brown K, Scales MK, Elhossiny AM, Espinoza CE, Lasse Opsahl EL, Griffith BD, Wen Y, Sun L, Velez-Delgado A, Renollet NM, Morales J, Nedzesky NM, Baliira RK, Menjivar RE, Medina-Cabrera PI, Rao A, Allen B, Shi J, Frankel TL, Carpenter ES, Bednar F, Zhang Y, Pasca di Magliano M. Donahue KL, et al. Cancer Discov. 2024 Oct 4;14(10):1964-1989. doi: 10.1158/2159-8290.CD-24-0100. Cancer Discov. 2024. PMID: 38958646 Free PMC article.
KRT17high/CXCL8+ Tumor Cells Display Both Classical and Basal Features and Regulate Myeloid Infiltration in the Pancreatic Cancer Microenvironment.
Carpenter ES, Kadiyala P, Elhossiny AM, Kemp SB, Li J, Steele NG, Nicolle R, Nwosu ZC, Freeman J, Dai H, Paglia D, Du W, Donahue K, Morales J, Medina-Cabrera PI, Bonilla ME, Harris L, The S, Gunchick V, Peterson N, Brown K, Mattea M, Espinoza CE, McGue J, Kabala SM, Baliira RK, Renollet NM, Mooney AG, Liu J, Bhalla S, Farida JP, Ko C, Machicado JD, Kwon RS, Wamsteker EJ, Schulman A, Anderson MA, Law R, Prabhu A, Coulombe PA, Rao A, Frankel TL, Bednar F, Shi J, Sahai V, Pasca Di Magliano M. Carpenter ES, et al. Clin Cancer Res. 2024 Jun 3;30(11):2497-2513. doi: 10.1158/1078-0432.CCR-23-1421. Clin Cancer Res. 2024. PMID: 37851080 Free PMC article.
Targeting glycans for CAR therapy: The advent of sweet CARs.
Raglow Z, McKenna MK, Bonifant CL, Wang W, Pasca di Magliano M, Stadlmann J, Penninger JM, Cummings RD, Brenner MK, Markovitz DM. Raglow Z, et al. Mol Ther. 2022 Sep 7;30(9):2881-2890. doi: 10.1016/j.ymthe.2022.07.006. Epub 2022 Jul 12. Mol Ther. 2022. PMID: 35821636 Free PMC article. Review.
Notch signaling regulates immunosuppressive tumor-associated macrophage function in pancreatic cancer.
Yan W, Steele NG, Kemp SB, Menjivar RE, Du W, Carpenter ES, Donahue KL, Brown KL, Irizarry-Negron V, Yang S, Burns WR 3rd, Zhang Y, di Magliano MP, Bednar F. Yan W, et al. bioRxiv [Preprint]. 2023 Jan 13:2023.01.11.523584. doi: 10.1101/2023.01.11.523584. bioRxiv. 2023. Update in: Cancer Immunol Res. 2024 Jan 3;12(1):91-106. doi: 10.1158/2326-6066.CIR-23-0037 PMID: 36711890 Free PMC article. Updated. Preprint.
Analysis of donor pancreata defines the transcriptomic signature and microenvironment of early pre-neoplastic pancreatic lesions.
Carpenter ES, Elhossiny AM, Kadiyala P, Li J, McGue J, Griffith B, Zhang Y, Edwards J, Nelson S, Lima F, Donahue KL, Du W, Bischoff AC, Alomari D, Watkoske H, Mattea M, The S, Espinoza C, Barrett M, Sonnenday CJ, Olden N, Peterson N, Gunchick V, Sahai V, Rao A, Bednar F, Shi J, Frankel TL, Di Magliano MP. Carpenter ES, et al. bioRxiv [Preprint]. 2023 Jan 15:2023.01.13.523300. doi: 10.1101/2023.01.13.523300. bioRxiv. 2023. Update in: Cancer Discov. 2023 Jun 2;13(6):1324-1345. doi: 10.1158/2159-8290.CD-23-0013 PMID: 36712058 Free PMC article. Updated. Preprint.