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ErbB2 induces Notch1 activity and function in breast cancer cells.
Lindsay J, Jiao X, Sakamaki T, Casimiro MC, Shirley LA, Tran TH, Ju X, Liu M, Li Z, Wang C, Katiyar S, Rao M, Allen KG, Glazer RI, Ge C, Stanley P, Lisanti MP, Rui H, Pestell RG. Lindsay J, et al. Clin Transl Sci. 2008 Sep;1(2):107-15. doi: 10.1111/j.1752-8062.2008.00041.x. Clin Transl Sci. 2008. PMID: 20443831 Free PMC article.
A reduction in Pten tumor suppressor activity promotes ErbB-2-induced mouse prostate adenocarcinoma formation through the activation of signaling cascades downstream of PDK1.
Rodriguez OC, Lai EW, Vissapragada S, Cromelin C, Avetian M, Salinas P, Ramos H, Kallakury B, Casimiro M, Lisanti MP, Tanowitz HB, Pacak K, Glazer RI, Avantaggiati M, Albanese C. Rodriguez OC, et al. Am J Pathol. 2009 Jun;174(6):2051-60. doi: 10.2353/ajpath.2009.080859. Epub 2009 May 14. Am J Pathol. 2009. PMID: 19443706 Free PMC article.