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Acylcarnitines activate proinflammatory signaling pathways.
Rutkowsky JM, Knotts TA, Ono-Moore KD, McCoin CS, Huang S, Schneider D, Singh S, Adams SH, Hwang DH. Rutkowsky JM, et al. Am J Physiol Endocrinol Metab. 2014 Jun 15;306(12):E1378-87. doi: 10.1152/ajpendo.00656.2013. Epub 2014 Apr 22. Am J Physiol Endocrinol Metab. 2014. PMID: 24760988 Free PMC article.
Improved metabolic health alters host metabolism in parallel with changes in systemic xeno-metabolites of gut origin.
Campbell C, Grapov D, Fiehn O, Chandler CJ, Burnett DJ, Souza EC, Casazza GA, Gustafson MB, Keim NL, Newman JW, Hunter GR, Fernandez JR, Garvey WT, Harper ME, Hoppel CL, Meissen JK, Take K, Adams SH. Campbell C, et al. PLoS One. 2014 Jan 8;9(1):e84260. doi: 10.1371/journal.pone.0084260. eCollection 2014. PLoS One. 2014. PMID: 24416208 Free PMC article. Clinical Trial.