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Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency.
Cacchiarelli D, Trapnell C, Ziller MJ, Soumillon M, Cesana M, Karnik R, Donaghey J, Smith ZD, Ratanasirintrawoot S, Zhang X, Ho Sui SJ, Wu Z, Akopian V, Gifford CA, Doench J, Rinn JL, Daley GQ, Meissner A, Lander ES, Mikkelsen TS. Cacchiarelli D, et al. Cell. 2015 Jul 16;162(2):412-424. doi: 10.1016/j.cell.2015.06.016. Cell. 2015. PMID: 26186193 Free PMC article.
Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma.
Powers JT, Tsanov KM, Pearson DS, Roels F, Spina CS, Ebright R, Seligson M, de Soysa Y, Cahan P, Theißen J, Tu HC, Han A, Kurek KC, LaPier GS, Osborne JK, Ross SJ, Cesana M, Collins JJ, Berthold F, Daley GQ. Powers JT, et al. Nature. 2016 Jul 14;535(7611):246-51. doi: 10.1038/nature18632. Epub 2016 Jul 6. Nature. 2016. PMID: 27383785 Free PMC article.
Precise let-7 expression levels balance organ regeneration against tumor suppression.
Wu L, Nguyen LH, Zhou K, de Soysa TY, Li L, Miller JB, Tian J, Locker J, Zhang S, Shinoda G, Seligson MT, Zeitels LR, Acharya A, Wang SC, Mendell JT, He X, Nishino J, Morrison SJ, Siegwart DJ, Daley GQ, Shyh-Chang N, Zhu H. Wu L, et al. Elife. 2015 Oct 7;4:e09431. doi: 10.7554/eLife.09431. Elife. 2015. PMID: 26445246 Free PMC article.
LIN28 cooperates with WNT signaling to drive invasive intestinal and colorectal adenocarcinoma in mice and humans.
Tu HC, Schwitalla S, Qian Z, LaPier GS, Yermalovich A, Ku YC, Chen SC, Viswanathan SR, Zhu H, Nishihara R, Inamura K, Kim SA, Morikawa T, Mima K, Sukawa Y, Yang J, Meredith G, Fuchs CS, Ogino S, Daley GQ. Tu HC, et al. Genes Dev. 2015 May 15;29(10):1074-86. doi: 10.1101/gad.256693.114. Epub 2015 May 8. Genes Dev. 2015. PMID: 25956904 Free PMC article.