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A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells.
Chem Biol. 2013 Jan 24;20(1):55-62. doi: 10.1016/j.chembiol.2012.10.016.
Chem Biol. 2013.
PMID: 23352139
Free PMC article.
Synthesis and SAR studies of 5-(pyridin-4-yl)-1,3,4-thiadiazol-2-amine derivatives as potent inhibitors of Bloom helicase.
Rosenthal AS, Dexheimer TS, Gileadi O, Nguyen GH, Chu WK, Hickson ID, Jadhav A, Simeonov A, Maloney DJ.
Rosenthal AS, et al.
Bioorg Med Chem Lett. 2013 Oct 15;23(20):5660-6. doi: 10.1016/j.bmcl.2013.08.025. Epub 2013 Aug 13.
Bioorg Med Chem Lett. 2013.
PMID: 24012121
Free PMC article.
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