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Identification of a Noxo1 inhibitor by addition of a polyethylene glycol chain.
Bioorg Med Chem. 2023 May 1;85:117274. doi: 10.1016/j.bmc.2023.117274. Epub 2023 Apr 5.
Bioorg Med Chem. 2023.
PMID: 37031566
Oxidative Cyclization-Induced Activation of a Phosphoinositide 3-Kinase Inhibitor for Enhanced Selectivity of Cancer Chemotherapeutics.
Zhu H, Mishra R, Yuan L, Abdul Salam SF, Liu J, Gray G, Sterling AD, Wunderlich M, Landero-Figueroa J, Garrett JT, Merino EJ.
Zhu H, et al.
ChemMedChem. 2019 Nov 20;14(22):1933-1939. doi: 10.1002/cmdc.201900481. Epub 2019 Nov 7.
ChemMedChem. 2019.
PMID: 31696673
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Phosphoinositide 3-Kinase (PI3K) Reactive Oxygen Species (ROS)-Activated Prodrug in Combination with Anthracycline Impairs PI3K Signaling, Increases DNA Damage Response and Reduces Breast Cancer Cell Growth.
Mishra R, Yuan L, Patel H, Karve AS, Zhu H, White A, Alanazi S, Desai P, Merino EJ, Garrett JT.
Mishra R, et al.
Int J Mol Sci. 2021 Feb 19;22(4):2088. doi: 10.3390/ijms22042088.
Int J Mol Sci. 2021.
PMID: 33669867
Free PMC article.
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