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Klebsiella pneumoniae clinical isolates with features of both multidrug-resistance and hypervirulence have unexpectedly low virulence.
Kochan TJ, Nozick SH, Valdes A, Mitra SD, Cheung BH, Lebrun-Corbin M, Medernach RL, Vessely MB, Mills JO, Axline CMR, Nelson JA, VanGosen EM, Ward TJ, Ozer EA, van Duin D, Chen L, Kreiswirth BN, Long SW, Musser JM, Bulman ZP, Wunderink RG, Hauser AR. Kochan TJ, et al. Nat Commun. 2023 Dec 2;14(1):7962. doi: 10.1038/s41467-023-43802-1. Nat Commun. 2023. PMID: 38042959 Free PMC article.
Genome-wide screens reveal shared and strain-specific genes that facilitate enteric colonization by Klebsiella pneumoniae.
Cheung BH, Alisoltani A, Kochan TJ, Lebrun-Corbin M, Nozick SH, Axline CM, Bachta KE, Ozer EA, Hauser AR. Cheung BH, et al. bioRxiv [Preprint]. 2023 Aug 31:2023.08.30.555643. doi: 10.1101/2023.08.30.555643. bioRxiv. 2023. Update in: mBio. 2023 Dec 19;14(6):e0212823. doi: 10.1128/mbio.02128-23 PMID: 37693543 Free PMC article. Updated. Preprint.