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Intestinal tuft cell immune privilege enables norovirus persistence.
Strine MS, Fagerberg E, Darcy PW, Barrón GM, Filler RB, Alfajaro MM, D'Angelo-Gavrish N, Wang F, Graziano VR, Menasché BL, Damo M, Wang YT, Howitt MR, Lee S, Joshi NS, Mucida D, Wilen CB. Strine MS, et al. Sci Immunol. 2024 Mar 22;9(93):eadi7038. doi: 10.1126/sciimmunol.adi7038. Epub 2024 Mar 22. Sci Immunol. 2024. PMID: 38517952 Free PMC article.
Tuft cell-derived acetylcholine regulates epithelial fluid secretion.
Billipp TE, Fung C, Webeck LM, Sargent DB, Gologorsky MB, McDaniel MM, Kasal DN, McGinty JW, Barrow KA, Rich LM, Barilli A, Sabat M, Debley JS, Myers R, Howitt MR, von Moltke J. Billipp TE, et al. bioRxiv [Preprint]. 2023 Mar 22:2023.03.17.533208. doi: 10.1101/2023.03.17.533208. bioRxiv. 2023. Update in: Immunity. 2024 Jun 11;57(6):1243-1259.e8. doi: 10.1016/j.immuni.2024.03.023 PMID: 36993541 Free PMC article. Updated. Preprint.
Tuft cells mediate commensal remodeling of the small intestinal antimicrobial landscape.
Fung C, Fraser LM, Barrón GM, Gologorsky MB, Atkinson SN, Gerrick ER, Hayward M, Ziegelbauer J, Li JA, Nico KF, Tyner MDW, DeSchepper LB, Pan A, Salzman NH, Howitt MR. Fung C, et al. Proc Natl Acad Sci U S A. 2023 Jun 6;120(23):e2216908120. doi: 10.1073/pnas.2216908120. Epub 2023 May 30. Proc Natl Acad Sci U S A. 2023. PMID: 37253002 Free PMC article.