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Melanoma models for the next generation of therapies.
Patton EE, Mueller KL, Adams DJ, Anandasabapathy N, Aplin AE, Bertolotto C, Bosenberg M, Ceol CJ, Burd CE, Chi P, Herlyn M, Holmen SL, Karreth FA, Kaufman CK, Khan S, Kobold S, Leucci E, Levy C, Lombard DB, Lund AW, Marie KL, Marine JC, Marais R, McMahon M, Robles-Espinoza CD, Ronai ZA, Samuels Y, Soengas MS, Villanueva J, Weeraratna AT, White RM, Yeh I, Zhu J, Zon LI, Hurlbert MS, Merlino G. Patton EE, et al. Cancer Cell. 2021 May 10;39(5):610-631. doi: 10.1016/j.ccell.2021.01.011. Epub 2021 Feb 4. Cancer Cell. 2021. PMID: 33545064 Free PMC article. Review.
SIRT5's GOT1 up on PDAC.
Kumar S, Lombard DB. Kumar S, et al. Gastroenterology. 2021 Nov;161(5):1376-1378. doi: 10.1053/j.gastro.2021.07.020. Epub 2021 Jul 16. Gastroenterology. 2021. PMID: 34280390 Free PMC article. No abstract available.
Epigenetic mechanisms of cadmium-induced nephrotoxicity.
Guo AH, Kumar S, Lombard DB. Guo AH, et al. Curr Opin Toxicol. 2022 Dec;32:100372. doi: 10.1016/j.cotox.2022.100372. Epub 2022 Oct 21. Curr Opin Toxicol. 2022. PMID: 37193357 Free PMC article.
Potent and Specific Activators for Mitochondrial Sirtuins Sirt3 and Sirt5.
Suenkel B, Valente S, Zwergel C, Weiss S, Di Bello E, Fioravanti R, Aventaggiato M, Amorim JA, Garg N, Kumar S, Lombard DB, Hu T, Singh PK, Tafani M, Palmeira CM, Sinclair D, Mai A, Steegborn C. Suenkel B, et al. J Med Chem. 2022 Oct 27;65(20):14015-14031. doi: 10.1021/acs.jmedchem.2c01215. Epub 2022 Oct 13. J Med Chem. 2022. PMID: 36228194 Free PMC article.