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The Enzymatic Activity of APOBE3G Multimers.
Pan Y, Zagorski K, Shlyakhtenko LS, Lyubchenko YL. Pan Y, et al. Sci Rep. 2018 Dec 18;8(1):17953. doi: 10.1038/s41598-018-36372-6. Sci Rep. 2018. PMID: 30560880 Free PMC article.
Assembly of α-synuclein aggregates on phospholipid bilayers.
Lv Z, Hashemi M, Banerjee S, Zagorski K, Rochet JC, Lyubchenko YL. Lv Z, et al. Biochim Biophys Acta Proteins Proteom. 2019 Sep;1867(9):802-812. doi: 10.1016/j.bbapap.2019.06.006. Epub 2019 Jun 19. Biochim Biophys Acta Proteins Proteom. 2019. PMID: 31226488 Free PMC article.
Testing a MultiTEP-based combination vaccine to reduce Aβ and tau pathology in Tau22/5xFAD bigenic mice.
Davtyan H, Hovakimyan A, Kiani Shabestari S, Antonyan T, Coburn MA, Zagorski K, Chailyan G, Petrushina I, Svystun O, Danhash E, Petrovsky N, Cribbs DH, Agadjanyan MG, Blurton-Jones M, Ghochikyan A. Davtyan H, et al. Alzheimers Res Ther. 2019 Dec 17;11(1):107. doi: 10.1186/s13195-019-0556-2. Alzheimers Res Ther. 2019. PMID: 31847886 Free PMC article.
A MultiTEP platform-based epitope vaccine targeting the phosphatase activating domain (PAD) of tau: therapeutic efficacy in PS19 mice.
Hovakimyan A, Antonyan T, Shabestari SK, Svystun O, Chailyan G, Coburn MA, Carlen-Jones W, Petrushina I, Chadarevian JP, Zagorski K, Petrovsky N, Cribbs DH, Agadjanyan MG, Ghochikyan A, Davtyan H. Hovakimyan A, et al. Sci Rep. 2019 Oct 29;9(1):15455. doi: 10.1038/s41598-019-51809-2. Sci Rep. 2019. PMID: 31664089 Free PMC article.
Active immunization with tau epitope in a mouse model of tauopathy induced strong antibody response together with improvement in short memory and pSer396-tau pathology.
Joly-Amado A, Davtyan H, Serraneau K, Jules P, Zitnyar A, Pressman E, Zagorski K, Antonyan T, Hovakimyan A, Paek HJ, Gordon MN, Cribbs DH, Petrovsky N, Agadjanyan MG, Ghochikyan A, Morgan D. Joly-Amado A, et al. Neurobiol Dis. 2020 Feb;134:104636. doi: 10.1016/j.nbd.2019.104636. Epub 2019 Oct 17. Neurobiol Dis. 2020. PMID: 31629891 Free PMC article.