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The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability.
Ravn-Boess N, Roy N, Hattori T, Bready D, Donaldson H, Lawson C, Lapierre C, Korman A, Rodrick T, Liu E, Frenster JD, Stephan G, Wilcox J, Corrado AD, Cai J, Ronnen R, Wang S, Haddock S, Sabio Ortiz J, Mishkit O, Khodadadi-Jamayran A, Tsirigos A, Fenyö D, Zagzag D, Drube J, Hoffmann C, Perna F, Jones DR, Possemato R, Koide A, Koide S, Park CY, Placantonakis DG. Ravn-Boess N, et al. Cell Rep. 2023 Nov 28;42(11):113374. doi: 10.1016/j.celrep.2023.113374. Epub 2023 Nov 8. Cell Rep. 2023. PMID: 37938973 Free PMC article.
PTK7 is a positive allosteric modulator of GPR133 signaling in glioblastoma.
Frenster JD, Erdjument-Bromage H, Stephan G, Ravn-Boess N, Wang S, Liu W, Bready D, Wilcox J, Kieslich B, Jankovic M, Wilde C, Horn S, Sträter N, Liebscher I, Schöneberg T, Fenyo D, Neubert TA, Placantonakis DG. Frenster JD, et al. Cell Rep. 2023 Jul 25;42(7):112679. doi: 10.1016/j.celrep.2023.112679. Epub 2023 Jun 23. Cell Rep. 2023. PMID: 37354459 Free PMC article.
Prognostic value of DNA methylation subclassification, aneuploidy, and CDKN2A/B homozygous deletion in predicting clinical outcome of IDH mutant astrocytomas.
Galbraith K, Garcia M, Wei S, Chen A, Schroff C, Serrano J, Pacione D, Placantonakis DG, William CM, Faustin A, Zagzag D, Barbaro M, Eibl MDPGP, Shirahata M, Reuss D, Tran QT, Alom Z, von Deimling A, Orr BA, Sulman EP, Golfinos JG, Orringer DA, Jain R, Lieberman E, Feng Y, Snuderl M. Galbraith K, et al. Neuro Oncol. 2024 Jun 3;26(6):1042-1051. doi: 10.1093/neuonc/noae009. Neuro Oncol. 2024. PMID: 38243818 Free PMC article.
Tractography passes the test: Results from the diffusion-simulated connectivity (disco) challenge.
Girard G, Rafael-Patiño J, Truffet R, Aydogan DB, Adluru N, Nair VA, Prabhakaran V, Bendlin BB, Alexander AL, Bosticardo S, Gabusi I, Ocampo-Pineda M, Battocchio M, Piskorova Z, Bontempi P, Schiavi S, Daducci A, Stafiej A, Ciupek D, Bogusz F, Pieciak T, Frigo M, Sedlar S, Deslauriers-Gauthier S, Kojčić I, Zucchelli M, Laghrissi H, Ji Y, Deriche R, Schilling KG, Landman BA, Cacciola A, Basile GA, Bertino S, Newlin N, Kanakaraj P, Rheault F, Filipiak P, Shepherd TM, Lin YC, Placantonakis DG, Boada FE, Baete SH, Hernández-Gutiérrez E, Ramírez-Manzanares A, Coronado-Leija R, Stack-Sánchez P, Concha L, Descoteaux M, Mansour L S, Seguin C, Zalesky A, Marshall K, Canales-Rodríguez EJ, Wu Y, Ahmad S, Yap PT, Théberge A, Gagnon F, Massi F, Fischi-Gomez E, Gardier R, Haro JLV, Pizzolato M, Caruyer E, Thiran JP. Girard G, et al. Neuroimage. 2023 Aug 15;277:120231. doi: 10.1016/j.neuroimage.2023.120231. Epub 2023 Jun 16. Neuroimage. 2023. PMID: 37330025 Free PMC article.
Modulation of GPR133 (ADGRD1) Signaling by its Intracellular Interaction Partner Extended Synaptotagmin 1 (ESYT1).
Stephan G, Erdjument-Bromage H, Liu W, Frenster JD, Ravn-Boess N, Bready D, Cai J, Fenyo D, Neubert T, Placantonakis DG. Stephan G, et al. bioRxiv [Preprint]. 2023 Feb 9:2023.02.09.527921. doi: 10.1101/2023.02.09.527921. bioRxiv. 2023. Update in: Cell Rep. 2024 May 28;43(5):114229. doi: 10.1016/j.celrep.2024.114229 PMID: 36798364 Free PMC article. Updated. Preprint.
Advances and Hurdles in CAR T Cell Immune Therapy for Solid Tumors.
Boccalatte F, Mina R, Aroldi A, Leone S, Suryadevara CM, Placantonakis DG, Bruno B. Boccalatte F, et al. Cancers (Basel). 2022 Oct 18;14(20):5108. doi: 10.3390/cancers14205108. Cancers (Basel). 2022. PMID: 36291891 Free PMC article. Review.
11 results