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Page 1
A small-molecule TrkB ligand improves dendritic spine phenotypes and atypical behaviors in female Rett syndrome mice.
Medeiros D, Ayala-Baylon K, Egido-Betancourt H, Miller E, Chapleau CA, Robinson HA, Phillips ML, Yang T, Longo F, Li W, Pozzo-Miller L. Medeiros D, et al. bioRxiv [Preprint]. 2023 Nov 17:2023.11.09.566435. doi: 10.1101/2023.11.09.566435. bioRxiv. 2023. Update in: Dis Model Mech. 2024 Jun 1;17(6):dmm050612. doi: 10.1242/dmm.050612 PMID: 37986936 Free PMC article. Updated. Preprint.
MAPT expression is mediated by long-range interactions with cis-regulatory elements.
Rogers BB, Anderson AG, Lauzon SN, Davis MN, Hauser RM, Roberts SC, Rodriguez-Nunez I, Trausch-Lowther K, Barinaga EA, Taylor JW, Mackiewicz M, Roberts BS, Cooper SJ, Rizzardi LF, Myers RM, Cochran JN. Rogers BB, et al. bioRxiv [Preprint]. 2023 Apr 11:2023.03.07.531520. doi: 10.1101/2023.03.07.531520. bioRxiv. 2023. Update in: Am J Hum Genet. 2024 Feb 1;111(2):259-279. doi: 10.1016/j.ajhg.2023.12.015 PMID: 37090552 Free PMC article. Updated. Preprint.
Patients with sporadic FTLD exhibit similar increases in lysosomal proteins and storage material as patients with FTD due to GRN mutations.
Davis SE, Cook AK, Hall JA, Voskobiynyk Y, Carullo NV, Boyle NR, Hakim AR, Anderson KM, Hobdy KP, Pugh DA, Murchison CF, McMeekin LJ, Simmons M, Margolies KA, Cowell RM, Nana AL, Spina S, Grinberg LT, Miller BL, Seeley WW, Arrant AE. Davis SE, et al. Acta Neuropathol Commun. 2023 Apr 28;11(1):70. doi: 10.1186/s40478-023-01571-4. Acta Neuropathol Commun. 2023. PMID: 37118844 Free PMC article.
The SINE Compound KPT-350 Blocks Dystrophic Pathologies in DMD Zebrafish and Mice.
Hightower RM, Reid AL, Gibbs DE, Wang Y, Widrick JJ, Kunkel LM, Kastenschmidt JM, Villalta SA, van Groen T, Chang H, Gornisiewicz S, Landesman Y, Tamir S, Alexander MS. Hightower RM, et al. Mol Ther. 2020 Jan 8;28(1):189-201. doi: 10.1016/j.ymthe.2019.08.016. Epub 2019 Sep 3. Mol Ther. 2020. PMID: 31628052 Free PMC article.
23 results