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A prion-like protein regulator of seed germination undergoes hydration-dependent phase separation.
Dorone Y, Boeynaems S, Flores E, Jin B, Hateley S, Bossi F, Lazarus E, Pennington JG, Michiels E, De Decker M, Vints K, Baatsen P, Bassel GW, Otegui MS, Holehouse AS, Exposito-Alonso M, Sukenik S, Gitler AD, Rhee SY. Dorone Y, et al. Cell. 2021 Aug 5;184(16):4284-4298.e27. doi: 10.1016/j.cell.2021.06.009. Epub 2021 Jul 6. Cell. 2021. PMID: 34233164 Free PMC article.
Structural biases in disordered proteins are prevalent in the cell.
Moses D, Guadalupe K, Yu F, Flores E, Perez AR, McAnelly R, Shamoon NM, Kaur G, Cuevas-Zepeda E, Merg AD, Martin EW, Holehouse AS, Sukenik S. Moses D, et al. Nat Struct Mol Biol. 2024 Feb;31(2):283-292. doi: 10.1038/s41594-023-01148-8. Epub 2024 Jan 4. Nat Struct Mol Biol. 2024. PMID: 38177684 Free PMC article.
Labile assembly of a tardigrade protein induces biostasis.
Sanchez-Martinez S, Nguyen K, Biswas S, Nicholson V, Romanyuk AV, Ramirez J, Kc S, Akter A, Childs C, Meese EK, Usher ET, Ginell GM, Yu F, Gollub E, Malferrari M, Francia F, Venturoli G, Martin EW, Caporaletti F, Giubertoni G, Woutersen S, Sukenik S, Woolfson DN, Holehouse AS, Boothby TC. Sanchez-Martinez S, et al. Protein Sci. 2024 Apr;33(4):e4941. doi: 10.1002/pro.4941. Protein Sci. 2024. PMID: 38501490 Free PMC article.
12 results