R35 GM139627/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2021	1
2022	3
2023	6
2024	1

1

Mechanistic perspectives on anti-aminoacyl-tRNA synthetase syndrome.

Kanaji S, Chen W, Morodomi Y, Shapiro R, Kanaji T, Yang XL. Kanaji S, et al. Trends Biochem Sci. 2023 Mar;48(3):288-302. doi: 10.1016/j.tibs.2022.09.011. Epub 2022 Oct 21. Trends Biochem Sci. 2023. PMID: 36280495 Free PMC article. Review.

2

Seryl-tRNA synthetase promotes translational readthrough by mRNA binding and involvement of the selenocysteine incorporation machinery.

Liu Z, Wang J, Shi Y, Yee BA, Terrey M, Zhang Q, Lee JC, Lin KI, Wang AH, Ackerman SL, Yeo GW, Cui H, Yang XL. Liu Z, et al. Nucleic Acids Res. 2023 Oct 27;51(19):10768-10781. doi: 10.1093/nar/gkad773. Nucleic Acids Res. 2023. PMID: 37739431 Free PMC article.

3

Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability.

Gioelli N, Neilson LJ, Wei N, Villari G, Chen W, Kuhle B, Ehling M, Maione F, Willox S, Brundu S, Avanzato D, Koulouras G, Mazzone M, Giraudo E, Yang XL, Valdembri D, Zanivan S, Serini G. Gioelli N, et al. Nat Commun. 2022 Jul 20;13(1):4188. doi: 10.1038/s41467-022-31904-1. Nat Commun. 2022. PMID: 35858913 Free PMC article.

4

CMT2D neuropathy is influenced by vitamin D-mediated environmental pathway.

Liu H, Tang M, Yu H, Liu T, Cui Q, Gu L, Wu ZY, Sheng N, Yang XL, Zeng L, Bai G. Liu H, et al. J Mol Cell Biol. 2023 Aug 3;15(4):mjad029. doi: 10.1093/jmcb/mjad029. J Mol Cell Biol. 2023. PMID: 37118880 Free PMC article. No abstract available.

5

Inflammatory platelet production stimulated by tyrosyl-tRNA synthetase mimicking viral infection.

Morodomi Y, Kanaji S, Sullivan BM, Zarpellon A, Orje JN, Won E, Shapiro R, Yang XL, Ruf W, Schimmel P, Ruggeri ZM, Kanaji T. Morodomi Y, et al. Proc Natl Acad Sci U S A. 2022 Nov 29;119(48):e2212659119. doi: 10.1073/pnas.2212659119. Epub 2022 Nov 21. Proc Natl Acad Sci U S A. 2022. PMID: 36409883 Free PMC article.

6

Boosting peripheral BDNF rescues impaired in vivo axonal transport in CMT2D mice.

Sleigh JN, Villarroel-Campos D, Surana S, Wickenden T, Tong Y, Simkin RL, Vargas JNS, Rhymes ER, Tosolini AP, West SJ, Zhang Q, Yang XL, Schiavo G. Sleigh JN, et al. JCI Insight. 2023 May 8;8(9):e157191. doi: 10.1172/jci.insight.157191. JCI Insight. 2023. PMID: 36928301 Free PMC article.

7

Domain collapse and active site ablation generate a widespread animal mitochondrial seryl-tRNA synthetase.

de Potter B, Vallee I, Camacho N, Filipe Costa Póvoas L, Bonsembiante A, Pons I Pons A, Eckhard U, Gomis-Rüth FX, Yang XL, Schimmel P, Kuhle B, Ribas de Pouplana L. de Potter B, et al. Nucleic Acids Res. 2023 Oct 13;51(18):10001-10010. doi: 10.1093/nar/gkad696. Nucleic Acids Res. 2023. PMID: 37638745 Free PMC article.

8

X-shaped structure of bacterial heterotetrameric tRNA synthetase suggests cryptic prokaryote functions and a rationale for synthetase classifications.

Ju Y, Han L, Chen B, Luo Z, Gu Q, Xu J, Yang XL, Schimmel P, Zhou H. Ju Y, et al. Nucleic Acids Res. 2021 Sep 27;49(17):10106-10119. doi: 10.1093/nar/gkab707. Nucleic Acids Res. 2021. PMID: 34390350 Free PMC article.

9

The binding mode of orphan glycyl-tRNA synthetase with tRNA supports the synthetase classification and reveals large domain movements.

Han L, Luo Z, Ju Y, Chen B, Zou T, Wang J, Xu J, Gu Q, Yang XL, Schimmel P, Zhou H. Han L, et al. Sci Adv. 2023 Feb 10;9(6):eadf1027. doi: 10.1126/sciadv.adf1027. Epub 2023 Feb 8. Sci Adv. 2023. PMID: 36753552 Free PMC article.

10

Boosting BDNF in muscle rescues impaired axonal transport in a mouse model of DI-CMTC peripheral neuropathy.

Rhymes ER, Simkin RL, Qu J, Villarroel-Campos D, Surana S, Tong Y, Shapiro R, Burgess RW, Yang XL, Schiavo G, Sleigh JN. Rhymes ER, et al. bioRxiv [Preprint]. 2024 Mar 11:2023.04.09.536152. doi: 10.1101/2023.04.09.536152. bioRxiv. 2024. Update in: Neurobiol Dis. 2024 Jun 1;195:106501. doi: 10.1016/j.nbd.2024.106501 PMID: 38559020 Free PMC article. Updated. Preprint.

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