R35 GM142486/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2022	1
2023	12
2024	7
2025	1

1

Bacterial esterases reverse lipopolysaccharide ubiquitylation to block host immunity.

Szczesna M, Huang Y, Lacoursiere RE, Bonini F, Pol V, Koc F, Ward B, Geurink PP, Pruneda JN, Thurston TLM. Szczesna M, et al. Cell Host Microbe. 2024 Jun 12;32(6):913-924.e7. doi: 10.1016/j.chom.2024.04.012. Cell Host Microbe. 2024. PMID: 38870903 Free article.

2

Bacterial ligases reveal fundamental principles of polyubiquitin specificity.

Franklin TG, Brzovic PS, Pruneda JN. Franklin TG, et al. Mol Cell. 2023 Dec 21;83(24):4538-4554.e4. doi: 10.1016/j.molcel.2023.11.017. Epub 2023 Dec 12. Mol Cell. 2023. PMID: 38091999 Free PMC article.

3

Ubiquitin-targeted bacterial effectors: rule breakers of the ubiquitin system.

Roberts CG, Franklin TG, Pruneda JN. Roberts CG, et al. EMBO J. 2023 Sep 18;42(18):e114318. doi: 10.15252/embj.2023114318. Epub 2023 Aug 9. EMBO J. 2023. PMID: 37555693 Free PMC article. Review.

4

Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays.

Pan X, Alvarez AN, Ma M, Lu S, Crawford MW, Briere LC, Kanca O, Yamamoto S, Sweetser DA, Wilson JL, Napier RJ, Pruneda JN, Bellen HJ. Pan X, et al. Elife. 2023 Dec 11;12:RP89891. doi: 10.7554/eLife.89891. Elife. 2023. PMID: 38079206 Free PMC article.

5

The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation.

Bastidas RJ, Kędzior M, Davidson RK, Walsh SC, Dolat L, Sixt BS, Pruneda JN, Coers J, Valdivia RH. Bastidas RJ, et al. Elife. 2024 Feb 15;12:RP87386. doi: 10.7554/eLife.87386. Elife. 2024. PMID: 38358795 Free PMC article.

6

Observing Real-Time Ubiquitination in High Throughput with Fluorescence Polarization.

Franklin TG, Pruneda JN. Franklin TG, et al. Methods Mol Biol. 2023;2581:3-12. doi: 10.1007/978-1-0716-2784-6_1. Methods Mol Biol. 2023. PMID: 36413306 Free PMC article.

7

Bacterial mimicry of eukaryotic HECT ubiquitin ligation.

Franklin TG, Brzovic PS, Pruneda JN. Franklin TG, et al. bioRxiv [Preprint]. 2023 Jun 5:2023.06.05.543783. doi: 10.1101/2023.06.05.543783. bioRxiv. 2023. Update in: Mol Cell. 2023 Dec 21;83(24):4538-4554.e4. doi: 10.1016/j.molcel.2023.11.017 PMID: 37333152 Free PMC article. Updated. Preprint.

8

Rapid turnover of CTLA4 is associated with a complex architecture of reversible ubiquitylation.

Tey PY, Dufner A, Knobeloch KP, Pruneda JN, Clague MJ, Urbé S. Tey PY, et al. bioRxiv [Preprint]. 2024 Jan 1:2023.12.31.573735. doi: 10.1101/2023.12.31.573735. bioRxiv. 2024. Update in: J Cell Biol. 2025 Jan 6;224(1):e202312141. doi: 10.1083/jcb.202312141 PMID: 38260548 Free PMC article. Updated. Preprint.

9

Bacterial usurpation of the OTU deubiquitinase fold.

Pruneda JN, Nguyen JV, Nagai H, Kubori T. Pruneda JN, et al. FEBS J. 2024 Aug;291(15):3303-3316. doi: 10.1111/febs.16725. Epub 2023 Jan 24. FEBS J. 2024. PMID: 36636866 Free PMC article. Review.

10

Dedicated bacterial esterases reverse lipopolysaccharide ubiquitylation to block immune sensing.

Szczesna M, Huang Y, Lacoursiere RE, Bonini F, Pol V, Koc F, Ward B, Geurink PP, Pruneda JN, Thurston TLM. Szczesna M, et al. Res Sq [Preprint]. 2023 Jul 12:rs.3.rs-2986327. doi: 10.21203/rs.3.rs-2986327/v1. Res Sq. 2023. Update in: Cell Host Microbe. 2024 Jun 12;32(6):913-924.e7. doi: 10.1016/j.chom.2024.04.012 PMID: 37503018 Free PMC article. Updated. Preprint.

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