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2023 4
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A Critical Role for ERO1α in Arterial Thrombosis and Ischemic Stroke.
Jha V, Xiong B, Kumari T, Brown G, Wang J, Kim K, Lee J, Asquith N, Gallagher J, Asherman L, Lambert T, Bai Y, Du X, Min JK, Sah R, Javaheri A, Razani B, Lee JM, Italiano JE, Cho J. Jha V, et al. Circ Res. 2023 May 26;132(11):e206-e222. doi: 10.1161/CIRCRESAHA.122.322473. Epub 2023 May 3. Circ Res. 2023. PMID: 37132383 Free PMC article.
The bone marrow is the primary site of thrombopoiesis.
Asquith NL, Carminita E, Camacho V, Rodriguez-Romera A, Stegner D, Freire D, Becker IC, Machlus KR, Khan AO, Italiano JE. Asquith NL, et al. Blood. 2024 Jan 18;143(3):272-278. doi: 10.1182/blood.2023020895. Blood. 2024. PMID: 37879046
Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36.
Barrachina MN, Pernes G, Becker IC, Allaeys I, Hirsch TI, Groeneveld DJ, Khan AO, Freire D, Guo K, Carminita E, Morgan PK, Collins TJ, Mellett NA, Wei Z, Almazni I, Italiano JE, Luyendyk J, Meikle PJ, Puder M, Morgan NV, Boilard E, Murphy AJ, Machlus KR. Barrachina MN, et al. bioRxiv [Preprint]. 2023 Feb 12:2023.02.12.527706. doi: 10.1101/2023.02.12.527706. bioRxiv. 2023. PMID: 36798332 Free PMC article. Updated. Preprint.
Cell cycle-dependent centrosome clustering precedes proplatelet formation.
Becker IC, Wilkie AR, Nikols E, Carminita E, Roweth HG, Tilburg J, Sciaudone AR, Noetzli LJ, Fatima F, Couldwell G, Ray A, Mogilner A, Machlus KR, Italiano JE Jr. Becker IC, et al. Sci Adv. 2024 Jun 21;10(25):eadl6153. doi: 10.1126/sciadv.adl6153. Epub 2024 Jun 19. Sci Adv. 2024. PMID: 38896608 Free PMC article.