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GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity.
Watson DC, Bayik D, Storevik S, Moreino SS, Sprowls SA, Han J, Augustsson MT, Lauko A, Sravya P, Røsland GV, Troike K, Tronstad KJ, Wang S, Sarnow K, Kay K, Lunavat TR, Silver DJ, Dayal S, Joseph JV, Mulkearns-Hubert E, Ystaas LAR, Deshpande G, Guyon J, Zhou Y, Magaut CR, Seder J, Neises L, Williford SE, Meiser J, Scott AJ, Sajjakulnukit P, Mears JA, Bjerkvig R, Chakraborty A, Daubon T, Cheng F, Lyssiotis CA, Wahl DR, Hjelmeland AB, Hossain JA, Miletic H, Lathia JD. Watson DC, et al. Nat Cancer. 2023 May;4(5):648-664. doi: 10.1038/s43018-023-00556-5. Epub 2023 May 11. Nat Cancer. 2023. PMID: 37169842 Free PMC article.
WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma.
Mitchell K, Sprowls SA, Arora S, Shakya S, Silver DJ, Goins CM, Wallace L, Roversi G, Schafer RE, Kay K, Miller TE, Lauko A, Bassett J, Kashyap A, D'Amato Kass J, Mulkearns-Hubert EE, Johnson S, Alvarado J, Rich JN, Holland EC, Paddison PJ, Patel AP, Stauffer SR, Hubert CG, Lathia JD. Mitchell K, et al. Genes Dev. 2023 Feb 1;37(3-4):86-102. doi: 10.1101/gad.349803.122. Epub 2023 Feb 2. Genes Dev. 2023. PMID: 36732025 Free PMC article.
Sex-Biased T-cell Exhaustion Drives Differential Immune Responses in Glioblastoma.
Lee J, Nicosia M, Hong ES, Silver DJ, Li C, Bayik D, Watson DC, Lauko A, Kay KE, Wang SZ, Johnson S, McGraw M, Grabowski MM, Kish DD, Desai AB, Goodman WA, Cameron SJ, Okada H, Valujskikh A, Fairchild RL, Ahluwalia MS, Lathia JD. Lee J, et al. Cancer Discov. 2023 Sep 6;13(9):2090-2105. doi: 10.1158/2159-8290.CD-22-0869. Cancer Discov. 2023. PMID: 37378557 Free PMC article.
'Slicing' glioblastoma drivers with the Swiss cheese model.
Teran Pumar OY, Lathia JD, Watson DC, Bayik D. Teran Pumar OY, et al. Trends Cancer. 2024 Jan;10(1):15-27. doi: 10.1016/j.trecan.2023.08.002. Epub 2023 Aug 23. Trends Cancer. 2024. PMID: 37625928 Free article. Review.
SerpinB3 drives cancer stem cell survival in glioblastoma.
Lauko A, Volovetz J, Turaga SM, Bayik D, Silver DJ, Mitchell K, Mulkearns-Hubert EE, Watson DC, Desai K, Midha M, Hao J, McCortney K, Steffens A, Naik U, Ahluwalia MS, Bao S, Horbinski C, Yu JS, Lathia JD. Lauko A, et al. Cell Rep. 2022 Sep 13;40(11):111348. doi: 10.1016/j.celrep.2022.111348. Cell Rep. 2022. PMID: 36103817 Free PMC article.
18 results