R35GM130322/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

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Pathogenic CANVAS (AAGGG)n repeats stall DNA replication due to the formation of alternative DNA structures.

Hisey JA, Radchenko EA, Mandel NH, McGinty RJ, Matos-Rodrigues G, Rastokina A, Masnovo C, Ceschi S, Hernandez A, Nussenzweig A, Mirkin SM. Hisey JA, et al. Nucleic Acids Res. 2024 May 8;52(8):4361-4374. doi: 10.1093/nar/gkae124. Nucleic Acids Res. 2024. PMID: 38381906 Free PMC article.

Massive contractions of myotonic dystrophy type 2-associated CCTG tetranucleotide repeats occur via double-strand break repair with distinct requirements for DNA helicases.

Papp D, Hernandez LA, Mai TA, Haanen TJ, O'Donnell MA, Duran AT, Hernandez SM, Narvanto JE, Arguello B, Onwukwe MO, Mirkin SM, Kim JC. Papp D, et al. G3 (Bethesda). 2024 Feb 7;14(2):jkad257. doi: 10.1093/g3journal/jkad257. G3 (Bethesda). 2024. PMID: 37950892 Free PMC article.

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