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Epidermal growth factor promotes protein degradation of epithelial protein lost in neoplasm (EPLIN), a putative metastasis suppressor, during epithelial-mesenchymal transition.
Zhang S, Wang X, Iqbal S, Wang Y, Osunkoya AO, Chen Z, Chen Z, Shin DM, Yuan H, Wang YA, Zhau HE, Chung LW, Ritenour C, Kucuk O, Wu D. Zhang S, et al. J Biol Chem. 2013 Jan 18;288(3):1469-79. doi: 10.1074/jbc.M112.438341. Epub 2012 Nov 27. J Biol Chem. 2013. PMID: 23188829 Free PMC article.
EPLIN downregulation promotes epithelial-mesenchymal transition in prostate cancer cells and correlates with clinical lymph node metastasis.
Zhang S, Wang X, Osunkoya AO, Iqbal S, Wang Y, Chen Z, Müller S, Chen Z, Josson S, Coleman IM, Nelson PS, Wang YA, Wang R, Shin DM, Marshall FF, Kucuk O, Chung LW, Zhau HE, Wu D. Zhang S, et al. Oncogene. 2011 Dec 15;30(50):4941-52. doi: 10.1038/onc.2011.199. Epub 2011 May 30. Oncogene. 2011. PMID: 21625216 Free PMC article.