R50 CA211399/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2016	2
2017	3
2018	5
2019	1
2020	5
2021	2
2022	3
2024	1

1

Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets.

Fu A, van Rooyen L, Evans L, Armstrong N, Avizonis D, Kin T, Bird GH, Reddy A, Chouchani ET, Liesa-Roig M, Walensky LD, Shapiro AMJ, Danial NN. Fu A, et al. Cell Rep. 2021 Nov 23;37(8):110037. doi: 10.1016/j.celrep.2021.110037. Cell Rep. 2021. PMID: 34818536 Free PMC article.

2

Hydrocarbon-Stitched Peptide Agonists of Glucagon-Like Peptide-1 Receptor.

Bird GH, Fu A, Escudero S, Godes M, Opoku-Nsiah K, Wales TE, Cameron MD, Engen JR, Danial NN, Walensky LD. Bird GH, et al. ACS Chem Biol. 2020 Jun 19;15(6):1340-1348. doi: 10.1021/acschembio.0c00308. Epub 2020 May 27. ACS Chem Biol. 2020. PMID: 32348108 Free PMC article.

3

Generation of Potent and Stable GLP-1 Analogues Via "Serine Ligation".

Levine PM, Craven TW, Li X, Balana AT, Bird GH, Godes M, Salveson PJ, Erickson PW, Lamb M, Ahlrichs M, Murphy M, Ogohara C, Said MY, Walensky LD, Pratt MR, Baker D. Levine PM, et al. ACS Chem Biol. 2022 Apr 15;17(4):804-809. doi: 10.1021/acschembio.2c00075. Epub 2022 Mar 23. ACS Chem Biol. 2022. PMID: 35319882 Free PMC article.

4

Glucose-dependent partitioning of arginine to the urea cycle protects β-cells from inflammation.

Fu A, Alvarez-Perez JC, Avizonis D, Kin T, Ficarro SB, Choi DW, Karakose E, Badur MG, Evans L, Rosselot C, Bridon G, Bird GH, Seo HS, Dhe-Paganon S, Kamphorst JJ, Stewart AF, James Shapiro AM, Marto JA, Walensky LD, Jones RG, Garcia-Ocana A, Danial NN. Fu A, et al. Nat Metab. 2020 May;2(5):432-446. doi: 10.1038/s42255-020-0199-4. Epub 2020 May 11. Nat Metab. 2020. PMID: 32694660 Free PMC article.

5

Paclitaxel Reduces Axonal Bclw to Initiate IP₃R1-Dependent Axon Degeneration.

Pease-Raissi SE, Pazyra-Murphy MF, Li Y, Wachter F, Fukuda Y, Fenstermacher SJ, Barclay LA, Bird GH, Walensky LD, Segal RA. Pease-Raissi SE, et al. Neuron. 2017 Oct 11;96(2):373-386.e6. doi: 10.1016/j.neuron.2017.09.034. Neuron. 2017. PMID: 29024661 Free PMC article.

6

Inhibition of FOXP3 by stapled alpha-helical peptides dampens regulatory T cell function.

Hawley KM, Eclov RJ, Schnorenberg MR, Tian Y, Shah RN, Thomas-Toth AT, Fefferman M, Bird GH, Walensky LD, Tirrell MV, LaBelle JL. Hawley KM, et al. Proc Natl Acad Sci U S A. 2022 Oct 18;119(42):e2209044119. doi: 10.1073/pnas.2209044119. Epub 2022 Oct 13. Proc Natl Acad Sci U S A. 2022. PMID: 36227917 Free PMC article.

7

Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival.

Fukuda Y, Pazyra-Murphy MF, Silagi ES, Tasdemir-Yilmaz OE, Li Y, Rose L, Yeoh ZC, Vangos NE, Geffken EA, Seo HS, Adelmant G, Bird GH, Walensky LD, Marto JA, Dhe-Paganon S, Segal RA. Fukuda Y, et al. J Cell Biol. 2021 Jan 4;220(1):e202005051. doi: 10.1083/jcb.202005051. J Cell Biol. 2021. PMID: 33284322 Free PMC article.

8

Structural basis for defective membrane targeting of mutant enzyme in human VLCAD deficiency.

Prew MS, Camara CM, Botzanowski T, Moroco JA, Bloch NB, Levy HR, Seo HS, Dhe-Paganon S, Bird GH, Herce HD, Gygi MA, Escudero S, Wales TE, Engen JR, Walensky LD. Prew MS, et al. Nat Commun. 2022 Jun 27;13(1):3669. doi: 10.1038/s41467-022-31466-2. Nat Commun. 2022. PMID: 35760926 Free PMC article.

9

Dissecting the neuroprotective interaction between the BH4 domain of BCL-w and the IP3 receptor.

Tang SX, Camara CM, Franco JA, Pazyra-Murphy MF, Li Y, Godes M, Moyer BM, Bird GH, Segal RA, Walensky LD. Tang SX, et al. Cell Chem Biol. 2024 Oct 17;31(10):1815-1826.e5. doi: 10.1016/j.chembiol.2024.06.016. Epub 2024 Jul 26. Cell Chem Biol. 2024. PMID: 39067448

10

Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in TP53 wild-type Ewing sarcoma.

Stolte B, Iniguez AB, Dharia NV, Robichaud AL, Conway AS, Morgan AM, Alexe G, Schauer NJ, Liu X, Bird GH, Tsherniak A, Vazquez F, Buhrlage SJ, Walensky LD, Stegmaier K. Stolte B, et al. J Exp Med. 2018 Aug 6;215(8):2137-2155. doi: 10.1084/jem.20171066. Epub 2018 Jul 25. J Exp Med. 2018. PMID: 30045945 Free PMC article.

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