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Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain.
Rayaprolu S, Bitarafan S, Santiago JV, Betarbet R, Sunna S, Cheng L, Xiao H, Nelson RS, Kumar P, Bagchi P, Duong DM, Goettemoeller AM, Oláh VJ, Rowan M, Levey AI, Wood LB, Seyfried NT, Rangaraju S. Rayaprolu S, et al. Nat Commun. 2022 May 25;13(1):2927. doi: 10.1038/s41467-022-30623-x. Nat Commun. 2022. PMID: 35614064 Free PMC article.
Native-state proteomics of Parvalbumin interneurons identifies unique molecular signatures and vulnerabilities to early Alzheimer's pathology.
Kumar P, Goettemoeller AM, Espinosa-Garcia C, Tobin BR, Tfaily A, Nelson RS, Natu A, Dammer EB, Santiago JV, Malepati S, Cheng L, Xiao H, Duong DD, Seyfried NT, Wood LB, Rowan MJM, Rangaraju S. Kumar P, et al. Nat Commun. 2024 Apr 1;15(1):2823. doi: 10.1038/s41467-024-47028-7. Nat Commun. 2024. PMID: 38561349 Free PMC article.
Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology.
Goettemoeller AM, Banks E, McCann KE, Kumar P, South K, Olah VJ, Ramelow CC, Duong DM, Seyfried NT, Rangaraju S, Weinshenker D, Rowan MJ. Goettemoeller AM, et al. Res Sq [Preprint]. 2023 Nov 6:rs.3.rs-3370607. doi: 10.21203/rs.3.rs-3370607/v1. Res Sq. 2023. Update in: Nat Commun. 2024 Sep 10;15(1):7918. doi: 10.1038/s41467-024-52297-3 PMID: 37987015 Free PMC article. Updated. Preprint.
Reducing voltage-dependent potassium channel Kv3.4 levels ameliorates synapse loss in a mouse model of Alzheimer's disease.
Yeap J, Sathyaprakash C, Toombs J, Tulloch J, Scutariu C, Rose J, Burr K, Davies C, Colom-Cadena M, Chandran S, Large CH, Rowan MJM, Gunthorpe MJ, Spires-Jones TL. Yeap J, et al. Brain Neurosci Adv. 2022 Mar 24;6:23982128221086464. doi: 10.1177/23982128221086464. eCollection 2022 Jan-Dec. Brain Neurosci Adv. 2022. PMID: 35359460 Free PMC article.
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