R56 AI076121/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2008	1
2009	1
2010	1
2011	2
2013	1
2019	1
2020	1
2021	4
2024	0

1

Inositol phosphates promote HIV-1 assembly and maturation to facilitate viral spread in human CD4+ T cells.

Sowd GA, Aiken C. Sowd GA, et al. PLoS Pathog. 2021 Jan 21;17(1):e1009190. doi: 10.1371/journal.ppat.1009190. eCollection 2021 Jan. PLoS Pathog. 2021. PMID: 33476323 Free PMC article.

2

HIV-1 CA Inhibitors Are Antagonized by Inositol Phosphate Stabilization of the Viral Capsid in Cells.

Sowd GA, Shi J, Aiken C. Sowd GA, et al. J Virol. 2021 Nov 23;95(24):e0144521. doi: 10.1128/JVI.01445-21. Epub 2021 Oct 6. J Virol. 2021. PMID: 34613803 Free PMC article.

3

Rhesus TRIM5α disrupts the HIV-1 capsid at the inter-hexamer interfaces.

Zhao G, Ke D, Vu T, Ahn J, Shah VB, Yang R, Aiken C, Charlton LM, Gronenborn AM, Zhang P. Zhao G, et al. PLoS Pathog. 2011 Mar;7(3):e1002009. doi: 10.1371/journal.ppat.1002009. Epub 2011 Mar 24. PLoS Pathog. 2011. PMID: 21455494 Free PMC article.

4

Curvature of the Retroviral Capsid Assembly Is Modulated by a Molecular Switch.

Thames T, Bryer AJ, Qiao X, Jeon J, Weed R, Janicki K, Hu B, Gor'kov PL, Hung I, Gan Z, Perilla JR, Chen B. Thames T, et al. J Phys Chem Lett. 2021 Aug 19;12(32):7768-7776. doi: 10.1021/acs.jpclett.1c01769. Epub 2021 Aug 10. J Phys Chem Lett. 2021. PMID: 34374542 Free PMC article.

5

HIV-1 uncoating occurs via a series of rapid biomechanical changes in the core related to individual stages of reverse transcription.

Rankovic S, Deshpande A, Harel S, Aiken C, Rousso I. Rankovic S, et al. J Virol. 2021 Apr 26;95(10):e00166-21. doi: 10.1128/JVI.00166-21. Epub 2021 Mar 10. J Virol. 2021. PMID: 33692202 Free PMC article.

6

PF74 Inhibits HIV-1 Integration by Altering the Composition of the Preintegration Complex.

Balasubramaniam M, Zhou J, Addai A, Martinez P, Pandhare J, Aiken C, Dash C. Balasubramaniam M, et al. J Virol. 2019 Mar 5;93(6):e01741-18. doi: 10.1128/JVI.01741-18. Print 2019 Mar 15. J Virol. 2019. PMID: 30567984 Free PMC article.

7

The Host Cell Metabolite Inositol Hexakisphosphate Promotes Efficient Endogenous HIV-1 Reverse Transcription by Stabilizing the Viral Capsid.

Jennings J, Shi J, Varadarajan J, Jamieson PJ, Aiken C. Jennings J, et al. mBio. 2020 Dec 1;11(6):e02820-20. doi: 10.1128/mBio.02820-20. mBio. 2020. PMID: 33262260 Free PMC article.

8

Biochemical characterization of a recombinant TRIM5alpha protein that restricts human immunodeficiency virus type 1 replication.

Langelier CR, Sandrin V, Eckert DM, Christensen DE, Chandrasekaran V, Alam SL, Aiken C, Olsen JC, Kar AK, Sodroski JG, Sundquist WI. Langelier CR, et al. J Virol. 2008 Dec;82(23):11682-94. doi: 10.1128/JVI.01562-08. Epub 2008 Sep 17. J Virol. 2008. PMID: 18799573 Free PMC article.

9

Structural convergence between Cryo-EM and NMR reveals intersubunit interactions critical for HIV-1 capsid function.

Byeon IJ, Meng X, Jung J, Zhao G, Yang R, Ahn J, Shi J, Concel J, Aiken C, Zhang P, Gronenborn AM. Byeon IJ, et al. Cell. 2009 Nov 13;139(4):780-90. doi: 10.1016/j.cell.2009.10.010. Cell. 2009. PMID: 19914170 Free PMC article.

10

Structure of the HIV-1 full-length capsid protein in a conformationally trapped unassembled state induced by small-molecule binding.

Du S, Betts L, Yang R, Shi H, Concel J, Ahn J, Aiken C, Zhang P, Yeh JI. Du S, et al. J Mol Biol. 2011 Feb 25;406(3):371-86. doi: 10.1016/j.jmb.2010.11.027. Epub 2010 Dec 10. J Mol Biol. 2011. PMID: 21146540 Free PMC article.

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