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Group A Streptococcus encounters with host macrophages.
Valderrama JA, Nizet V. Valderrama JA, et al. Future Microbiol. 2018 Jan;13(1):119-134. doi: 10.2217/fmb-2017-0142. Epub 2017 Dec 11. Future Microbiol. 2018. PMID: 29226710 Free PMC article. Review.
Strengthening of enterococcal biofilms by Esp.
Spiegelman L, Bahn-Suh A, Montaño ET, Zhang L, Hura GL, Patras KA, Kumar A, Tezcan FA, Nizet V, Tsutakawa SE, Ghosh P. Spiegelman L, et al. PLoS Pathog. 2022 Sep 14;18(9):e1010829. doi: 10.1371/journal.ppat.1010829. eCollection 2022 Sep. PLoS Pathog. 2022. PMID: 36103556 Free PMC article.
Group A streptococcal M protein activates the NLRP3 inflammasome.
Valderrama JA, Riestra AM, Gao NJ, LaRock CN, Gupta N, Ali SR, Hoffman HM, Ghosh P, Nizet V. Valderrama JA, et al. Nat Microbiol. 2017 Oct;2(10):1425-1434. doi: 10.1038/s41564-017-0005-6. Epub 2017 Aug 7. Nat Microbiol. 2017. PMID: 28784982 Free PMC article.
IL-1β is an innate immune sensor of microbial proteolysis.
LaRock CN, Todd J, LaRock DL, Olson J, O'Donoghue AJ, Robertson AA, Cooper MA, Hoffman HM, Nizet V. LaRock CN, et al. Sci Immunol. 2016 Aug;1(2):eaah3539. doi: 10.1126/sciimmunol.aah3539. Epub 2016 Aug 19. Sci Immunol. 2016. PMID: 28331908 Free PMC article.