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En masse organoid phenotyping informs metabolic-associated genetic susceptibility to NASH.
Kimura M, Iguchi T, Iwasawa K, Dunn A, Thompson WL, Yoneyama Y, Chaturvedi P, Zorn AM, Wintzinger M, Quattrocelli M, Watanabe-Chailland M, Zhu G, Fujimoto M, Kumbaji M, Kodaka A, Gindin Y, Chung C, Myers RP, Subramanian GM, Hwa V, Takebe T. Kimura M, et al. Cell. 2022 Oct 27;185(22):4216-4232.e16. doi: 10.1016/j.cell.2022.09.031. Epub 2022 Oct 13. Cell. 2022. PMID: 36240780 Free PMC article.
Transcriptional programming of translation by BCL6 controls skeletal muscle proteostasis.
Ramachandran K, Futtner CR, Sommars MA, Quattrocelli M, Omura Y, Fruzyna E, Wang JC, Waldeck NJ, Senagolage MD, Telles CG, Demonbreun AR, Prendergast E, Lai N, Arango D, Bederman IR, McNally EM, Barish GD. Ramachandran K, et al. Nat Metab. 2024 Feb;6(2):304-322. doi: 10.1038/s42255-024-00983-3. Epub 2024 Feb 9. Nat Metab. 2024. PMID: 38337096 Free PMC article.
A fat- and sucrose-enriched diet causes metabolic alterations in mdx mice.
Krishna S, Echevarria KG, Reed CH, Eo H, Wintzinger M, Quattrocelli M, Valentine RJ, Selsby JT. Krishna S, et al. Am J Physiol Regul Integr Comp Physiol. 2023 Dec 1;325(6):R692-R711. doi: 10.1152/ajpregu.00246.2022. Epub 2023 Oct 9. Am J Physiol Regul Integr Comp Physiol. 2023. PMID: 37811713 Free PMC article.
Anti-latent TGFβ binding protein 4 antibody improves muscle function and reduces muscle fibrosis in muscular dystrophy.
Demonbreun AR, Fallon KS, Oosterbaan CC, Vaught LA, Reiser NL, Bogdanovic E, Velez MP, Salamone IM, Page PGT, Hadhazy M, Quattrocelli M, Barefield DY, Wood LD, Gonzalez JP, Morris C, McNally EM. Demonbreun AR, et al. Sci Transl Med. 2021 Sep 8;13(610):eabf0376. doi: 10.1126/scitranslmed.abf0376. Epub 2021 Sep 8. Sci Transl Med. 2021. PMID: 34516828 Free PMC article.
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