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2023 5
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Indole-3-Propionic Acid, a Gut Microbiota Metabolite, Protects Against the Development of Postoperative Delirium.
Zhou X, Wu X, Wu Y, Yang L, Shi E, Ding W, Chen L, Shi X, Feng X, Su C, You Z, Xia J, Chen C, Yeliseyev V, Bry L, Xia S, Huang P, Meng J, Houle T, Akeju O, Mao J, Gerszten R, Chen Q, Xie Z, Shen S. Zhou X, et al. Ann Surg. 2023 Dec 1;278(6):e1164-e1174. doi: 10.1097/SLA.0000000000005886. Epub 2023 Apr 27. Ann Surg. 2023. PMID: 37185230 Free PMC article.
Development and Pharmacochemical Characterization Discover a Novel Brain-Permeable HDAC11-Selective Inhibitor with Therapeutic Potential by Regulating Neuroinflammation in Mice.
Bai P, Liu Y, Yang L, Ding W, Mondal P, Sang N, Liu G, Lu X, Ho TT, Zhou Y, Wu R, Birar VC, Wilks MQ, Tanzi RE, Lin H, Zhang C, Li W, Shen S, Wang C. Bai P, et al. J Med Chem. 2023 Dec 14;66(23):16075-16090. doi: 10.1021/acs.jmedchem.3c01491. Epub 2023 Nov 16. J Med Chem. 2023. PMID: 37972387
Highly synchronized cortical circuit dynamics mediate spontaneous pain in mice.
Ding W, Fischer L, Chen Q, Li Z, Yang L, You Z, Hu K, Wu X, Zhou X, Chao W, Hu P, Dagnew TM, Dubreuil DM, Wang S, Xia S, Bao C, Zhu S, Chen L, Wang C, Wainger B, Jin P, Mao J, Feng G, Harnett MT, Shen S. Ding W, et al. J Clin Invest. 2023 Mar 1;133(5):e166408. doi: 10.1172/JCI166408. J Clin Invest. 2023. PMID: 36602876 Free PMC article.
Aging-associated decrease of PGC-1α promotes pain chronification.
Wu X, Yang L, Li Z, Gu C, Jin K, Luo A, Rasheed NF, Fiutak I, Chao K, Chen A, Mao J, Chen Q, Ding W, Shen S. Wu X, et al. Aging Cell. 2024 Aug;23(8):e14177. doi: 10.1111/acel.14177. Epub 2024 May 17. Aging Cell. 2024. PMID: 38760908 Free PMC article.