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Chemopreventive sphingadienes downregulate Wnt signaling via a PP2A/Akt/GSK3β pathway in colon cancer.
Carcinogenesis. 2012 Sep;33(9):1726-35. doi: 10.1093/carcin/bgs174. Epub 2012 May 11.
Carcinogenesis. 2012.
PMID: 22581840
Free PMC article.
Natural sphingadienes inhibit Akt-dependent signaling and prevent intestinal tumorigenesis.
Fyrst H, Oskouian B, Bandhuvula P, Gong Y, Byun HS, Bittman R, Lee AR, Saba JD.
Fyrst H, et al.
Cancer Res. 2009 Dec 15;69(24):9457-64. doi: 10.1158/0008-5472.CAN-09-2341.
Cancer Res. 2009.
PMID: 19934323
Free PMC article.
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