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Evaluation of potential PET imaging probes for the orexin 2 receptors.
Wang C, Wilson CM, Moseley CK, Carlin SM, Hsu S, Arabasz G, Schroeder FA, Sander CY, Hooker JM. Wang C, et al. Nucl Med Biol. 2013 Nov;40(8):1000-5. doi: 10.1016/j.nucmedbio.2013.07.001. Epub 2013 Aug 15. Nucl Med Biol. 2013. PMID: 23953751 Free PMC article.
PET imaging demonstrates histone deacetylase target engagement and clarifies brain penetrance of known and novel small molecule inhibitors in rat.
Schroeder FA, Wang C, Van de Bittner GC, Neelamegam R, Takakura WR, Karunakaran A, Wey HY, Reis SA, Gale J, Zhang YL, Holson EB, Haggarty SJ, Hooker JM. Schroeder FA, et al. ACS Chem Neurosci. 2014 Oct 15;5(10):1055-62. doi: 10.1021/cn500162j. Epub 2014 Sep 19. ACS Chem Neurosci. 2014. PMID: 25188794 Free PMC article.