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A universal definition of ARDS: the PaO2/FiO2 ratio under a standard ventilatory setting--a prospective, multicenter validation study.
Villar J, Pérez-Méndez L, Blanco J, Añón JM, Blanch L, Belda J, Santos-Bouza A, Fernández RL, Kacmarek RM; Spanish Initiative for Epidemiology, Stratification, and Therapies for ARDS (SIESTA) Network. Villar J, et al. Among authors: santos bouza a. Intensive Care Med. 2013 Apr;39(4):583-92. doi: 10.1007/s00134-012-2803-x. Epub 2013 Jan 31. Intensive Care Med. 2013. PMID: 23370826
A clinical classification of the acute respiratory distress syndrome for predicting outcome and guiding medical therapy*.
Villar J, Fernández RL, Ambrós A, Parra L, Blanco J, Domínguez-Berrot AM, Gutiérrez JM, Blanch L, Añón JM, Martín C, Prieto F, Collado J, Pérez-Méndez L, Kacmarek RM; Acute Lung Injury Epidemiology and Natural history Network. Villar J, et al. Crit Care Med. 2015 Feb;43(2):346-53. doi: 10.1097/CCM.0000000000000703. Crit Care Med. 2015. PMID: 25393701
A risk tertiles model for predicting mortality in patients with acute respiratory distress syndrome: age, plateau pressure, and P(aO(2))/F(IO(2)) at ARDS onset can predict mortality.
Villar J, Pérez-Méndez L, Basaldúa S, Blanco J, Aguilar G, Toral D, Zavala E, Romera MA, González-Díaz G, Nogal FD, Santos-Bouza A, Ramos L, Macías S, Kacmarek RM; Hospitales Españoles Para el Estudio de la Lesión Pulmonar (HELP) Network*. Villar J, et al. Among authors: santos bouza a. Respir Care. 2011 Apr;56(4):420-8. doi: 10.4187/respcare.00811. Epub 2011 Jan 21. Respir Care. 2011. PMID: 21255500 Free article.
Assessment of PaO₂/FiO₂ for stratification of patients with moderate and severe acute respiratory distress syndrome.
Villar J, Blanco J, del Campo R, Andaluz-Ojeda D, Díaz-Domínguez FJ, Muriel A, Córcoles V, Suárez-Sipmann F, Tarancón C, González-Higueras E, López J, Blanch L, Pérez-Méndez L, Fernández RL, Kacmarek RM; Spanish Initiative for Epidemiology, Stratification & Therapies for ARDS (SIESTA) Network. Villar J, et al. BMJ Open. 2015 Mar 27;5(3):e006812. doi: 10.1136/bmjopen-2014-006812. BMJ Open. 2015. PMID: 25818272 Free PMC article. Clinical Trial.
The ALIEN study: incidence and outcome of acute respiratory distress syndrome in the era of lung protective ventilation.
Villar J, Blanco J, Añón JM, Santos-Bouza A, Blanch L, Ambrós A, Gandía F, Carriedo D, Mosteiro F, Basaldúa S, Fernández RL, Kacmarek RM; ALIEN Network. Villar J, et al. Among authors: santos bouza a. Intensive Care Med. 2011 Dec;37(12):1932-41. doi: 10.1007/s00134-011-2380-4. Epub 2011 Oct 14. Intensive Care Med. 2011. PMID: 21997128