Discovery of Natural Potent HMG-CoA Reductase Degraders for Lowering Cholesterol.
Su XZ, Zhang LF, Hu K, An Y, Zhang QP, Tang JW, Yan BC, Li XR, Cai J, Li XN, Sun HD, Jiang SY, Puno PT.
Su XZ, et al.
Angew Chem Int Ed Engl. 2024 Feb 5;63(6):e202313859. doi: 10.1002/anie.202313859. Epub 2023 Dec 20.
Angew Chem Int Ed Engl. 2024.
PMID: 38055195
DG23, which inhabits the key protected wild plant Schisandra macrocarpa. Chemical studies on the cultures of this strain afforded eight novel indole diterpenoids, schipenindolenes A-H (1-8), belonging to six diverse skeleton types. ...
DG23, which inhabits the key protected wild plant Schisandra macrocarpa. Chemical studies on the cultures of this strain afforded eig …