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Page 1
CSF proteomics identifies early changes in autosomal dominant Alzheimer's disease.
Shen Y, Timsina J, Heo G, Beric A, Ali M, Wang C, Yang C, Wang Y, Western D, Liu M, Gorijala P, Budde J, Do A, Liu H, Gordon B, Llibre-Guerra JJ, Joseph-Mathurin N, Perrin RJ, Maschi D, Wyss-Coray T, Pastor P, Renton AE, Surace EI, Johnson ECB, Levey AI, Alvarez I, Levin J, Ringman JM, Allegri RF, Seyfried N, Day GS, Wu Q, Fernández MV, Tarawneh R, McDade E, Morris JC, Bateman RJ, Goate A; Dominantly Inherited Alzheimer Network; Ibanez L, Sung YJ, Cruchaga C. Shen Y, et al. Cell. 2024 Oct 31;187(22):6309-6326.e15. doi: 10.1016/j.cell.2024.08.049. Epub 2024 Sep 26. Cell. 2024. PMID: 39332414 Free PMC article.
The case for low-level BACE1 inhibition for the prevention of Alzheimer disease.
McDade E, Voytyuk I, Aisen P, Bateman RJ, Carrillo MC, De Strooper B, Haass C, Reiman EM, Sperling R, Tariot PN, Yan R, Masters CL, Vassar R, Lichtenthaler SF. McDade E, et al. Nat Rev Neurol. 2021 Nov;17(11):703-714. doi: 10.1038/s41582-021-00545-1. Epub 2021 Sep 21. Nat Rev Neurol. 2021. PMID: 34548654 Review.
15 Years of Longitudinal Genetic, Clinical, Cognitive, Imaging, and Biochemical Measures in DIAN.
Daniels AJ, McDade E, Llibre-Guerra JJ, Xiong C, Perrin RJ, Ibanez L, Supnet-Bell C, Cruchaga C, Goate A, Renton AE, Benzinger TLS, Gordon BA, Hassenstab J, Karch C, Popp B, Levey A, Morris J, Buckles V, Allegri RF, Chrem P, Berman SB, Chhatwal JP, Farlow MR, Fox NC, Day GS, Ikeuchi T, Jucker M, Lee JH, Levin J, Lopera F, Takada L, Sosa AL, Martins R, Mori H, Noble JM, Salloway S, Huey E, Rosa-Neto P, Sánchez-Valle R, Schofield PR, Roh JH, Bateman RJ; Dominantly Inherited Alzheimer Network. Daniels AJ, et al. medRxiv [Preprint]. 2024 Aug 9:2024.08.08.24311689. doi: 10.1101/2024.08.08.24311689. medRxiv. 2024. PMID: 39148846 Free PMC article. Preprint.
Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN).
McKay NS, Gordon BA, Hornbeck RC, Dincer A, Flores S, Keefe SJ, Joseph-Mathurin N, Jack CR, Koeppe R, Millar PR, Ances BM, Chen CD, Daniels A, Hobbs DA, Jackson K, Koudelis D, Massoumzadeh P, McCullough A, Nickels ML, Rahmani F, Swisher L, Wang Q, Allegri RF, Berman SB, Brickman AM, Brooks WS, Cash DM, Chhatwal JP, Day GS, Farlow MR, la Fougère C, Fox NC, Fulham M, Ghetti B, Graff-Radford N, Ikeuchi T, Klunk W, Lee JH, Levin J, Martins R, Masters CL, McConathy J, Mori H, Noble JM, Reischl G, Rowe C, Salloway S, Sanchez-Valle R, Schofield PR, Shimada H, Shoji M, Su Y, Suzuki K, Vöglein J, Yakushev I, Cruchaga C, Hassenstab J, Karch C, McDade E, Perrin RJ, Xiong C, Morris JC, Bateman RJ, Benzinger TLS; Dominantly Inherited Alzheimer Network. McKay NS, et al. Nat Neurosci. 2023 Aug;26(8):1449-1460. doi: 10.1038/s41593-023-01359-8. Epub 2023 Jul 10. Nat Neurosci. 2023. PMID: 37429916 Free PMC article.
Covariance-based vs. correlation-based functional connectivity dissociates healthy aging from Alzheimer disease.
Strain JF, Brier MR, Tanenbaum A, Gordon BA, McCarthy JE, Dincer A, Marcus DS, Chhatwal JP, Graff-Radford NR, Day GS, la Fougère C, Perrin RJ, Salloway S, Schofield PR, Yakushev I, Ikeuchi T, Vöglein J, Morris JC, Benzinger TLS, Bateman RJ, Ances BM, Snyder AZ; Dominantly Inherited Alzheimer Network. Strain JF, et al. Neuroimage. 2022 Nov 1;261:119511. doi: 10.1016/j.neuroimage.2022.119511. Epub 2022 Jul 30. Neuroimage. 2022. PMID: 35914670 Free PMC article.
Biphasic cortical macro- and microstructural changes in autosomal dominant Alzheimer's disease.
Montal V, Vilaplana E, Pegueroles J, Bejanin A, Alcolea D, Carmona-Iragui M, Clarimón J, Levin J, Cruchaga C, Graff-Radford NR, Noble JM, Lee JH, Allegri R, Karch CM, Laske C, Schofield PR, Salloway S, Ances B, Benzinger T, McDale E, Bateman R, Blesa R, Sánchez-Valle R, Lleó A, Fortea J; Dominantly Inherited Alzheimer Network (DIAN). Montal V, et al. Alzheimers Dement. 2021 Apr;17(4):618-628. doi: 10.1002/alz.12224. Epub 2020 Nov 16. Alzheimers Dement. 2021. PMID: 33196147 Free PMC article.