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Chromatin accessibility profiling by ATAC-seq.
Grandi FC, Modi H, Kampman L, Corces MR. Grandi FC, et al. Nat Protoc. 2022 Jun;17(6):1518-1552. doi: 10.1038/s41596-022-00692-9. Epub 2022 Apr 27. Nat Protoc. 2022. PMID: 35478247 Free PMC article. Review.
Understanding the molecular basis of resilience to Alzheimer's disease.
Montine KS, Berson E, Phongpreecha T, Huang Z, Aghaeepour N, Zou JY, MacCoss MJ, Montine TJ. Montine KS, et al. Front Neurosci. 2023 Dec 19;17:1311157. doi: 10.3389/fnins.2023.1311157. eCollection 2023. Front Neurosci. 2023. PMID: 38192507 Free PMC article. Review.
Whole genome deconvolution unveils Alzheimer's resilient epigenetic signature.
Berson E, Sreenivas A, Phongpreecha T, Perna A, Grandi FC, Xue L, Ravindra NG, Payrovnaziri N, Mataraso S, Kim Y, Espinosa C, Chang AL, Becker M, Montine KS, Fox EJ, Chang HY, Corces MR, Aghaeepour N, Montine TJ. Berson E, et al. Nat Commun. 2023 Aug 16;14(1):4947. doi: 10.1038/s41467-023-40611-4. Nat Commun. 2023. PMID: 37587197 Free PMC article.
Integration of transcriptomics and long-read genomics prioritizes structural variants in rare disease.
Jensen TD, Ni B, Reuter CM, Gorzynski JE, Fazal S, Bonner D, Ungar RA, Goddard PC, Raja A, Ashley EA, Bernstein JA, Zuchner S; Undiagnosed Diseases Network; Greicius MD, Montgomery SB, Schatz MC, Wheeler MT, Battle A. Jensen TD, et al. medRxiv [Preprint]. 2024 Mar 26:2024.03.22.24304565. doi: 10.1101/2024.03.22.24304565. medRxiv. 2024. PMID: 38585781 Free PMC article. Preprint.
Integration of rare expression outlier-associated variants improves polygenic risk prediction.
Smail C, Ferraro NM, Hui Q, Durrant MG, Aguirre M, Tanigawa Y, Keever-Keigher MR, Rao AS, Justesen JM, Li X, Gloudemans MJ, Assimes TL, Kooperberg C, Reiner AP, Huang J, O'Donnell CJ, Sun YV; Million Veteran Program; Rivas MA, Montgomery SB. Smail C, et al. Am J Hum Genet. 2022 Jun 2;109(6):1055-1064. doi: 10.1016/j.ajhg.2022.04.015. Epub 2022 May 18. Am J Hum Genet. 2022. PMID: 35588732 Free PMC article.