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47 results

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Page 1
Preventing Engrailed-1 activation in fibroblasts yields wound regeneration without scarring.
Mascharak S, desJardins-Park HE, Davitt MF, Griffin M, Borrelli MR, Moore AL, Chen K, Duoto B, Chinta M, Foster DS, Shen AH, Januszyk M, Kwon SH, Wernig G, Wan DC, Lorenz HP, Gurtner GC, Longaker MT. Mascharak S, et al. Science. 2021 Apr 23;372(6540):eaba2374. doi: 10.1126/science.aba2374. Science. 2021. PMID: 33888614 Free PMC article.
Identification of the Human Skeletal Stem Cell.
Chan CKF, Gulati GS, Sinha R, Tompkins JV, Lopez M, Carter AC, Ransom RC, Reinisch A, Wearda T, Murphy M, Brewer RE, Koepke LS, Marecic O, Manjunath A, Seo EY, Leavitt T, Lu WJ, Nguyen A, Conley SD, Salhotra A, Ambrosi TH, Borrelli MR, Siebel T, Chan K, Schallmoser K, Seita J, Sahoo D, Goodnough H, Bishop J, Gardner M, Majeti R, Wan DC, Goodman S, Weissman IL, Chang HY, Longaker MT. Chan CKF, et al. Cell. 2018 Sep 20;175(1):43-56.e21. doi: 10.1016/j.cell.2018.07.029. Cell. 2018. PMID: 30241615 Free PMC article.
Articular cartilage regeneration by activated skeletal stem cells.
Murphy MP, Koepke LS, Lopez MT, Tong X, Ambrosi TH, Gulati GS, Marecic O, Wang Y, Ransom RC, Hoover MY, Steininger H, Zhao L, Walkiewicz MP, Quarto N, Levi B, Wan DC, Weissman IL, Goodman SB, Yang F, Longaker MT, Chan CKF. Murphy MP, et al. Nat Med. 2020 Oct;26(10):1583-1592. doi: 10.1038/s41591-020-1013-2. Epub 2020 Aug 17. Nat Med. 2020. PMID: 32807933 Free PMC article.
Aged skeletal stem cells generate an inflammatory degenerative niche.
Ambrosi TH, Marecic O, McArdle A, Sinha R, Gulati GS, Tong X, Wang Y, Steininger HM, Hoover MY, Koepke LS, Murphy MP, Sokol J, Seo EY, Tevlin R, Lopez M, Brewer RE, Mascharak S, Lu L, Ajanaku O, Conley SD, Seita J, Morri M, Neff NF, Sahoo D, Yang F, Weissman IL, Longaker MT, Chan CKF. Ambrosi TH, et al. Nature. 2021 Sep;597(7875):256-262. doi: 10.1038/s41586-021-03795-7. Epub 2021 Aug 11. Nature. 2021. PMID: 34381212 Free PMC article.
Immunomodulatory Microneedle Patch for Periodontal Tissue Regeneration.
Zhang X, Hasani-Sadrabadi MM, Zarubova J, Dashtimighadam E, Haghniaz R, Khademhosseini A, Butte MJ, Moshaverinia A, Aghaloo T, Li S. Zhang X, et al. Matter. 2022 Feb 2;5(2):666-682. doi: 10.1016/j.matt.2021.11.017. Epub 2021 Dec 8. Matter. 2022. PMID: 35340559 Free PMC article.
Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis.
Shkhyan R, Flynn C, Lamoure E, Sarkar A, Van Handel B, Li J, York J, Banks N, Van der Horst R, Liu NQ, Lee S, Bajaj P, Vadivel K, Harn HI, Tassey J, Lozito T, Lieberman JR, Chuong CM, Hurtig MS, Evseenko D. Shkhyan R, et al. Sci Transl Med. 2023 Mar 22;15(688):eabq2395. doi: 10.1126/scitranslmed.abq2395. Epub 2023 Mar 22. Sci Transl Med. 2023. PMID: 36947594 Free PMC article.
Purification and functional characterization of novel human skeletal stem cell lineages.
Hoover MY, Ambrosi TH, Steininger HM, Koepke LS, Wang Y, Zhao L, Murphy MP, Alam AA, Arouge EJ, Butler MGK, Takematsu E, Stavitsky SP, Hu S, Sahoo D, Sinha R, Morri M, Neff N, Bishop J, Gardner M, Goodman S, Longaker M, Chan CKF. Hoover MY, et al. Nat Protoc. 2023 Jul;18(7):2256-2282. doi: 10.1038/s41596-023-00836-5. Epub 2023 Jun 14. Nat Protoc. 2023. PMID: 37316563 Free PMC article. Review.
47 results