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Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma.
Osman AA, Arslan E, Bartels M, Michikawa C, Lindemann A, Tomczak K, Yu W, Sandulache V, Ma W, Shen L, Wang J, Singh AK, Frederick MJ, Spencer ND, Kovacs J, Heffernan T, Symmans WF, Rai K, Myers JN. Osman AA, et al. Clin Cancer Res. 2023 Apr 3;29(7):1344-1359. doi: 10.1158/1078-0432.CCR-22-2747. Clin Cancer Res. 2023. PMID: 36689560 Free PMC article.
FAK Drives Resistance to Therapy in HPV-Negative Head and Neck Cancer in a p53-Dependent Manner.
Pifer PM, Yang L, Kumar M, Xie T, Frederick M, Hefner A, Beadle B, Molkentine D, Molkentine J, Dhawan A, Abdelhakiem M, Osman AA, Leibowitz BJ, Myers JN, Pickering CR, Sandulache VC, Heymach J, Skinner HD. Pifer PM, et al. Clin Cancer Res. 2024 Jan 5;30(1):187-197. doi: 10.1158/1078-0432.CCR-23-0964. Clin Cancer Res. 2024. PMID: 37819945 Free PMC article.
Evolution of cisplatin resistance through coordinated metabolic reprogramming of the cellular reductive state.
Yu W, Chen Y, Putluri N, Osman A, Coarfa C, Putluri V, Kamal AHM, Asmussen JK, Katsonis P, Myers JN, Lai SY, Lu W, Stephan CC, Powell RT, Johnson FM, Skinner HD, Kazi J, Ahmed KM, Hu L, Threet A, Meyer MD, Bankson JA, Wang T, Davis J, Parker KR, Harris MA, Baek ML, Echeverria GV, Qi X, Wang J, Frederick AI, Walsh AJ, Lichtarge O, Frederick MJ, Sandulache VC. Yu W, et al. Br J Cancer. 2023 Jun;128(11):2013-2024. doi: 10.1038/s41416-023-02253-7. Epub 2023 Apr 3. Br J Cancer. 2023. PMID: 37012319 Free PMC article.
First-in-Human Hyperpolarized MRI for Tumor Metabolism in HNSCC.
Lai SY, Sandulache VC, Schellingerhout D, Fuller CD, Chen Y, Walker CM, Bankson JA. Lai SY, et al. JAMA Otolaryngol Head Neck Surg. 2024 Jul 1;150(7):628-630. doi: 10.1001/jamaoto.2024.1129. JAMA Otolaryngol Head Neck Surg. 2024. PMID: 38780963 Free PMC article.