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Year Number of Results
2008 2
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104 results

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Page 1
Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.
Sykes DB, Kfoury YS, Mercier FE, Wawer MJ, Law JM, Haynes MK, Lewis TA, Schajnovitz A, Jain E, Lee D, Meyer H, Pierce KA, Tolliday NJ, Waller A, Ferrara SJ, Eheim AL, Stoeckigt D, Maxcy KL, Cobert JM, Bachand J, Szekely BA, Mukherjee S, Sklar LA, Kotz JD, Clish CB, Sadreyev RI, Clemons PA, Janzer A, Schreiber SL, Scadden DT. Sykes DB, et al. Cell. 2016 Sep 22;167(1):171-186.e15. doi: 10.1016/j.cell.2016.08.057. Epub 2016 Sep 15. Cell. 2016. PMID: 27641501 Free PMC article.
BDDCS applied to over 900 drugs.
Benet LZ, Broccatelli F, Oprea TI. Benet LZ, et al. AAPS J. 2011 Dec;13(4):519-47. doi: 10.1208/s12248-011-9290-9. Epub 2011 Aug 5. AAPS J. 2011. PMID: 21818695 Free PMC article.
Flow Cytometry: Impact on Early Drug Discovery.
Edwards BS, Sklar LA. Edwards BS, et al. J Biomol Screen. 2015 Jul;20(6):689-707. doi: 10.1177/1087057115578273. Epub 2015 Mar 24. J Biomol Screen. 2015. PMID: 25805180 Free PMC article. Review.
Targeting efflux pumps to overcome antifungal drug resistance.
Holmes AR, Cardno TS, Strouse JJ, Ivnitski-Steele I, Keniya MV, Lackovic K, Monk BC, Sklar LA, Cannon RD. Holmes AR, et al. Future Med Chem. 2016 Aug;8(12):1485-501. doi: 10.4155/fmc-2016-0050. Epub 2016 Jul 27. Future Med Chem. 2016. PMID: 27463566 Free PMC article. Review.
The significance of acid/base properties in drug discovery.
Manallack DT, Prankerd RJ, Yuriev E, Oprea TI, Chalmers DK. Manallack DT, et al. Chem Soc Rev. 2013 Jan 21;42(2):485-96. doi: 10.1039/c2cs35348b. Chem Soc Rev. 2013. PMID: 23099561 Free PMC article. Review.
A Pan-GTPase Inhibitor as a Molecular Probe.
Hong L, Guo Y, BasuRay S, Agola JO, Romero E, Simpson DS, Schroeder CE, Simons P, Waller A, Garcia M, Carter M, Ursu O, Gouveia K, Golden JE, Aubé J, Wandinger-Ness A, Sklar LA. Hong L, et al. PLoS One. 2015 Aug 6;10(8):e0134317. doi: 10.1371/journal.pone.0134317. eCollection 2015. PLoS One. 2015. PMID: 26247207 Free PMC article.
104 results