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Rapid generation of potent antibodies by autonomous hypermutation in yeast.
Wellner A, McMahon C, Gilman MSA, Clements JR, Clark S, Nguyen KM, Ho MH, Hu VJ, Shin JE, Feldman J, Hauser BM, Caradonna TM, Wingler LM, Schmidt AG, Marks DS, Abraham J, Kruse AC, Liu CC. Wellner A, et al. Nat Chem Biol. 2021 Oct;17(10):1057-1064. doi: 10.1038/s41589-021-00832-4. Epub 2021 Jun 24. Nat Chem Biol. 2021. PMID: 34168368 Free PMC article.
We applied AHEAD to generate potent nanobodies against the SARS-CoV-2 S glycoprotein, a G-protein-coupled receptor and other targets, offering a template for streamlined antibody generation at large....
We applied AHEAD to generate potent nanobodies against the SARS-CoV-2 S glycoprotein, a G-protein-coupled receptor and …
Early life adversity and adolescent sleep problems during the COVID-19 pandemic.
Bridgewater JM, Berzenski SR, Doan SN, Yates TM. Bridgewater JM, et al. Stress Health. 2024 Jun;40(3):e3332. doi: 10.1002/smi.3332. Epub 2023 Oct 18. Stress Health. 2024. PMID: 37853922
The COVID-19 pandemic resulted in a reorganization of adolescents' routines, especially their sleep schedules. Utilising 175 caregiver-adolescent dyads, the current study examined associations of biological (e.g., prenatal substance use), environmental (e.g., povert …
The COVID-19 pandemic resulted in a reorganization of adolescents' routines, especially their sleep schedules. Utilising 175 c …