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2017 1
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Page 1
Genetic risk converges on regulatory networks mediating early type 2 diabetes.
Walker JT, Saunders DC, Rai V, Chen HH, Orchard P, Dai C, Pettway YD, Hopkirk AL, Reihsmann CV, Tao Y, Fan S, Shrestha S, Varshney A, Petty LE, Wright JJ, Ventresca C, Agarwala S, Aramandla R, Poffenberger G, Jenkins R, Mei S, Hart NJ, Phillips S, Kang H, Greiner DL, Shultz LD, Bottino R, Liu J, Below JE; HPAP Consortium; Parker SCJ, Powers AC, Brissova M. Walker JT, et al. Nature. 2023 Dec;624(7992):621-629. doi: 10.1038/s41586-023-06693-2. Epub 2023 Dec 4. Nature. 2023. PMID: 38049589 Free PMC article.
Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetes.
Wang G, Chiou J, Zeng C, Miller M, Matta I, Han JY, Kadakia N, Okino ML, Beebe E, Mallick M, Camunas-Soler J, Dos Santos T, Dai XQ, Ellis C, Hang Y, Kim SK, MacDonald PE, Kandeel FR, Preissl S, Gaulton KJ, Sander M. Wang G, et al. Nat Genet. 2023 Jun;55(6):984-994. doi: 10.1038/s41588-023-01397-9. Epub 2023 May 25. Nat Genet. 2023. PMID: 37231096 Free PMC article.
The Human Islet: Mini-Organ With Mega-Impact.
Walker JT, Saunders DC, Brissova M, Powers AC. Walker JT, et al. Endocr Rev. 2021 Sep 28;42(5):605-657. doi: 10.1210/endrev/bnab010. Endocr Rev. 2021. PMID: 33844836 Free PMC article. Review.
Identification of unique cell type responses in pancreatic islets to stress.
Maestas MM, Ishahak M, Augsornworawat P, Veronese-Paniagua DA, Maxwell KG, Velazco-Cruz L, Marquez E, Sun J, Shunkarova M, Gale SE, Urano F, Millman JR. Maestas MM, et al. Nat Commun. 2024 Jul 2;15(1):5567. doi: 10.1038/s41467-024-49724-w. Nat Commun. 2024. PMID: 38956087 Free PMC article.
Pancreatic islet α cell function and proliferation requires the arginine transporter SLC7A2.
Spears E, Stanley JE, Shou M, Yin L, Li X, Dai C, Bradley A, Sellick K, Poffenberger G, Coate KC, Shrestha S, Jenkins R, Sloop KW, Wilson KT, Attie AD, Keller MP, Chen W, Powers AC, Dean ED. Spears E, et al. bioRxiv [Preprint]. 2023 Aug 14:2023.08.10.552656. doi: 10.1101/2023.08.10.552656. bioRxiv. 2023. PMID: 37645716 Free PMC article. Preprint.
Pancreatic islet reserve in type 1 diabetes.
Flatt AJS, Greenbaum CJ, Shaw JAM, Rickels MR. Flatt AJS, et al. Ann N Y Acad Sci. 2021 Jul;1495(1):40-54. doi: 10.1111/nyas.14572. Epub 2021 Feb 6. Ann N Y Acad Sci. 2021. PMID: 33550589 Free PMC article. Review.
Adaptation to chronic ER stress enforces pancreatic β-cell plasticity.
Chen CW, Guan BJ, Alzahrani MR, Gao Z, Gao L, Bracey S, Wu J, Mbow CA, Jobava R, Haataja L, Zalavadia AH, Schaffer AE, Lee H, LaFramboise T, Bederman I, Arvan P, Mathews CE, Gerling IC, Kaestner KH, Tirosh B, Engin F, Hatzoglou M. Chen CW, et al. Nat Commun. 2022 Aug 8;13(1):4621. doi: 10.1038/s41467-022-32425-7. Nat Commun. 2022. PMID: 35941159 Free PMC article.
Multivariate indicators of disease severity in COVID-19.
Bean J, Kuri-Cervantes L, Pennella M, Betts MR, Meyer NJ, Hassan WM. Bean J, et al. Sci Rep. 2023 Mar 29;13(1):5145. doi: 10.1038/s41598-023-31683-9. Sci Rep. 2023. PMID: 36991002 Free PMC article.
63 results