ZIA DA000424/ImNIH/Intramural NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2017	1
2019	4
2020	3
2021	5
2022	1
2023	5
2024	2

1

Pharmacological targeting of G protein-coupled receptor heteromers.

Moreno E, Casajuana-Martin N, Coyle M, Campos BC, Galaj E, Del Torrent CL, Seyedian A, Rea W, Cai NS, Bonifazi A, Florán B, Xi ZX, Guitart X, Casadó V, Newman AH, Bishop C, Pardo L, Ferré S. Moreno E, et al. Pharmacol Res. 2022 Nov;185:106476. doi: 10.1016/j.phrs.2022.106476. Epub 2022 Sep 28. Pharmacol Res. 2022. PMID: 36182040 Free PMC article.

2

Pharmacological and Physicochemical Properties Optimization for Dual-Target Dopamine D₃ (D₃R) and μ-Opioid (MOR) Receptor Ligands as Potentially Safer Analgesics.

Bonifazi A, Saab E, Sanchez J, Nazarova AL, Zaidi SA, Jahan K, Katritch V, Canals M, Lane JR, Newman AH. Bonifazi A, et al. J Med Chem. 2023 Aug 10;66(15):10304-10341. doi: 10.1021/acs.jmedchem.3c00417. Epub 2023 Jul 19. J Med Chem. 2023. PMID: 37467430 Free PMC article.

3

3,4-Methylenedioxypyrovalerone High-Responder Phenotype as a Tool to Evaluate Candidate Medications for Stimulant Use Disorder.

Doyle MR, Peng LN, Cao J, Rice KC, Newman AH, Collins GT. Doyle MR, et al. J Pharmacol Exp Ther. 2023 Mar;384(3):353-362. doi: 10.1124/jpet.122.001419. Epub 2023 Jan 10. J Pharmacol Exp Ther. 2023. PMID: 36627204 Free PMC article.

4

Presynaptic and Postsynaptic Mesolimbic Dopamine D₃ Receptors Play Distinct Roles in Cocaine Versus Opioid Reward in Mice.

Xi ZX, Bocarsly ME, Galaj E, Hempel B, Teresi C, Shaw M, Bi GH, Jordan C, Linz E, Alton H, Tanda G, Freyberg Z, Alvarez VA, Newman AH. Xi ZX, et al. Biol Psychiatry. 2024 Nov 1;96(9):752-765. doi: 10.1016/j.biopsych.2024.05.020. Epub 2024 Jun 3. Biol Psychiatry. 2024. PMID: 38838841

5

Chiral Cyclic Aliphatic Linkers as Building Blocks for Selective Dopamine D₂ or D₃ Receptor Agonists.

Battiti FO, Zaidi SA, Katritch V, Newman AH, Bonifazi A. Battiti FO, et al. J Med Chem. 2021 Nov 11;64(21):16088-16105. doi: 10.1021/acs.jmedchem.1c01433. Epub 2021 Oct 26. J Med Chem. 2021. PMID: 34699207 Free PMC article.

6

New Drugs, Old Targets: Tweaking the Dopamine System to Treat Psychostimulant Use Disorders.

Newman AH, Ku T, Jordan CJ, Bonifazi A, Xi ZX. Newman AH, et al. Annu Rev Pharmacol Toxicol. 2021 Jan 6;61:609-628. doi: 10.1146/annurev-pharmtox-030220-124205. Annu Rev Pharmacol Toxicol. 2021. PMID: 33411583 Free PMC article.

7

Investigation of Novel Primary and Secondary Pharmacophores and 3-Substitution in the Linking Chain of a Series of Highly Selective and Bitopic Dopamine D₃ Receptor Antagonists and Partial Agonists.

Shaik AB, Kumar V, Bonifazi A, Guerrero AM, Cemaj SL, Gadiano A, Lam J, Xi ZX, Rais R, Slusher BS, Newman AH. Shaik AB, et al. J Med Chem. 2019 Oct 24;62(20):9061-9077. doi: 10.1021/acs.jmedchem.9b00607. Epub 2019 Oct 15. J Med Chem. 2019. PMID: 31526003 Free PMC article.

8

Structure Activity Relationships for a Series of Eticlopride-Based Dopamine D₂/D₃ Receptor Bitopic Ligands.

Shaik AB, Boateng CA, Battiti FO, Bonifazi A, Cao J, Chen L, Chitsazi R, Ravi S, Lee KH, Shi L, Newman AH. Shaik AB, et al. J Med Chem. 2021 Oct 28;64(20):15313-15333. doi: 10.1021/acs.jmedchem.1c01353. Epub 2021 Oct 12. J Med Chem. 2021. PMID: 34636551 Free PMC article.

9

Novel Dual-Target μ-Opioid Receptor and Dopamine D₃ Receptor Ligands as Potential Nonaddictive Pharmacotherapeutics for Pain Management.

Bonifazi A, Battiti FO, Sanchez J, Zaidi SA, Bow E, Makarova M, Cao J, Shaik AB, Sulima A, Rice KC, Katritch V, Canals M, Lane JR, Newman AH. Bonifazi A, et al. J Med Chem. 2021 Jun 10;64(11):7778-7808. doi: 10.1021/acs.jmedchem.1c00611. Epub 2021 May 20. J Med Chem. 2021. PMID: 34011153 Free PMC article.

10

Dopamine D₃/D₂ Receptor Ligands Based on Cariprazine for the Treatment of Psychostimulant Use Disorders That May Be Dual Diagnosed with Affective Disorders.

Gogarnoiu ES, Vogt CD, Sanchez J, Bonifazi A, Saab E, Shaik AB, Soler-Cedeño O, Bi GH, Klein B, Xi ZX, Lane JR, Newman AH. Gogarnoiu ES, et al. J Med Chem. 2023 Feb 9;66(3):1809-1834. doi: 10.1021/acs.jmedchem.2c01624. Epub 2023 Jan 20. J Med Chem. 2023. PMID: 36661568 Free PMC article.

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