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The ADAR1 editome reveals drivers of editing-specificity for ADAR1-isoforms.
Kleinova R, Rajendra V, Leuchtenberger AF, Lo Giudice C, Vesely C, Kapoor U, Tanzer A, Derdak S, Picardi E, Jantsch MF. Kleinova R, et al. Nucleic Acids Res. 2023 May 22;51(9):4191-4207. doi: 10.1093/nar/gkad265. Nucleic Acids Res. 2023. PMID: 37026479 Free PMC article.
ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology.
Gawish R, Starkl P, Pimenov L, Hladik A, Lakovits K, Oberndorfer F, Cronin SJ, Ohradanova-Repic A, Wirnsberger G, Agerer B, Endler L, Capraz T, Perthold JW, Cikes D, Koglgruber R, Hagelkruys A, Montserrat N, Mirazimi A, Boon L, Stockinger H, Bergthaler A, Oostenbrink C, Penninger JM, Knapp S. Gawish R, et al. Elife. 2022 Jan 13;11:e74623. doi: 10.7554/eLife.74623. Elife. 2022. PMID: 35023830 Free PMC article.
The Parkinson's drug entacapone disrupts gut microbiome homeostasis via iron sequestration.
Pereira FC, Ge X, Kristensen JM, Kirkegaard RH, Maritsch K, Zhu Y, Decorte M, Hausmann B, Berry D, Wasmund K, Schintlmeister A, Boettcher T, Cheng JX, Wagner M. Pereira FC, et al. bioRxiv [Preprint]. 2023 Nov 13:2023.11.12.566429. doi: 10.1101/2023.11.12.566429. bioRxiv. 2023. Update in: Nat Microbiol. 2024 Dec;9(12):3165-3183. doi: 10.1038/s41564-024-01853-0 PMID: 38014294 Free PMC article. Updated. Preprint.
Development of an aerosol intervention for COVID-19 disease: Tolerability of soluble ACE2 (APN01) administered via nebulizer.
Shoemaker RH, Panettieri RA Jr, Libutti SK, Hochster HS, Watts NR, Wingfield PT, Starkl P, Pimenov L, Gawish R, Hladik A, Knapp S, Boring D, White JM, Lawrence Q, Boone J, Marshall JD, Matthews RL, Cholewa BD, Richig JW, Chen BT, McCormick DL, Gugensberger R, Höller S, Penninger JM, Wirnsberger G. Shoemaker RH, et al. PLoS One. 2022 Jul 11;17(7):e0271066. doi: 10.1371/journal.pone.0271066. eCollection 2022. PLoS One. 2022. PMID: 35816490 Free PMC article.
Lung transplantation for COVID-19-associated acute respiratory distress syndrome in a PCR-positive patient.
Lang C, Jaksch P, Hoda MA, Lang G, Staudinger T, Tschernko E, Zapletal B, Geleff S, Prosch H, Gawish R, Knapp S, Robak O, Thalhammer F, Indra A, Koestenberger M, Strassl R, Klikovits T, Ali K, Fischer G, Klepetko W, Hoetzenecker K, Schellongowski P. Lang C, et al. Lancet Respir Med. 2020 Oct;8(10):1057-1060. doi: 10.1016/S2213-2600(20)30361-1. Epub 2020 Aug 25. Lancet Respir Med. 2020. PMID: 32857987 Free PMC article. No abstract available.