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Germline variants and advanced colorectal adenomas: adenoma prevention with celecoxib trial genome-wide association study.
Wang J, Carvajal-Carmona LG, Chu JH, Zauber AG; APC Trial Collaborators; Kubo M, Matsuda K, Dunlop M, Houlston RS, Sieber O, Lipton L, Gibbs P, Martin NG, Montgomery GW, Young J, Baird PN, Ratain MJ, Nakamura Y, Weiss ST, Tomlinson I, Bertagnolli MM. Wang J, et al. Clin Cancer Res. 2013 Dec 1;19(23):6430-7. doi: 10.1158/1078-0432.CCR-13-0550. Epub 2013 Oct 1. Clin Cancer Res. 2013. PMID: 24084763 Free PMC article.
Much of the genetic risk of colorectal cancer is likely to be mediated through susceptibility to adenomas.
Carvajal-Carmona LG, Zauber AG, Jones AM, Howarth K, Wang J, Cheng T; APC Trial Collaborators; APPROVe Trial Collaborators; CORGI Study Collaborators; Colon Cancer Family Registry Collaborators; CGEMS Collaborators; Riddell R, Lanas A, Morton D, Bertagnolli MM, Tomlinson I. Carvajal-Carmona LG, et al. Gastroenterology. 2013 Jan;144(1):53-5. doi: 10.1053/j.gastro.2012.09.016. Epub 2012 Sep 19. Gastroenterology. 2013. PMID: 22999960 Free PMC article.