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Page 1
Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis.
Jarvis JN, Lawrence DS, Meya DB, Kagimu E, Kasibante J, Mpoza E, Rutakingirwa MK, Ssebambulidde K, Tugume L, Rhein J, Boulware DR, Mwandumba HC, Moyo M, Mzinganjira H, Kanyama C, Hosseinipour MC, Chawinga C, Meintjes G, Schutz C, Comins K, Singh A, Muzoora C, Jjunju S, Nuwagira E, Mosepele M, Leeme T, Siamisang K, Ndhlovu CE, Hlupeni A, Mutata C, van Widenfelt E, Chen T, Wang D, Hope W, Boyer-Chammard T, Loyse A, Molloy SF, Youssouf N, Lortholary O, Lalloo DG, Jaffar S, Harrison TS; Ambition Study Group. Jarvis JN, et al. N Engl J Med. 2022 Mar 24;386(12):1109-1120. doi: 10.1056/NEJMoa2111904. N Engl J Med. 2022. PMID: 35320642 Free PMC article. Clinical Trial.
Development and validation of quantitative PCR assays for HIV-associated cryptococcal meningitis in sub-Saharan Africa: a diagnostic accuracy study.
Mbangiwa T, Sturny-Leclère A, Lechiile K, Kajanga C, Boyer-Chammard T, Hoving JC, Leeme T, Moyo M, Youssouf N, Lawrence DS, Mwandumba H, Mosepele M, Harrison TS, Jarvis JN, Lortholary O, Alanio A; AMBITION Study Group. Mbangiwa T, et al. Lancet Microbe. 2024 Mar;5(3):e261-e271. doi: 10.1016/S2666-5247(23)00362-2. Epub 2024 Feb 8. Lancet Microbe. 2024. PMID: 38342110 Free PMC article.
Cost-effectiveness of single, high-dose, liposomal amphotericin regimen for HIV-associated cryptococcal meningitis in five countries in sub-Saharan Africa: an economic analysis of the AMBITION-cm trial.
Lawrence DS, Muthoga C, Meya DB, Tugume L, Williams D, Rajasingham R, Boulware DR, Mwandumba HC, Moyo M, Dziwani EN, Maheswaran H, Kanyama C, Hosseinipour MC, Chawinga C, Meintjes G, Schutz C, Comins K, Bango F, Muzoora C, Jjunju S, Nuwagira E, Mosepele M, Leeme T, Ndhlovu CE, Hlupeni A, Shamu S, Boyer-Chammard T, Molloy SF, Youssouf N, Chen T, Shiri T, Jaffar S, Harrison TS, Jarvis JN, Niessen LW; AMBITION Study Group. Lawrence DS, et al. Lancet Glob Health. 2022 Dec;10(12):e1845-e1854. doi: 10.1016/S2214-109X(22)00450-8. Lancet Glob Health. 2022. PMID: 36400090 Free PMC article.
5-Flucytosine Longitudinal Antifungal Susceptibility Testing of Cryptococcus neoformans: A Substudy of the EnACT Trial Testing Oral Amphotericin.
McHale TC, Akampurira A, Gerlach ES, Mucunguzi A, Nicol MR, Williams DA, Nielsen K, Bicanic T, Fieberg A, Dai B, Meya DB, Boulware DR; ENACT Trial Team. McHale TC, et al. Open Forum Infect Dis. 2023 Nov 29;10(12):ofad596. doi: 10.1093/ofid/ofad596. eCollection 2023 Dec. Open Forum Infect Dis. 2023. PMID: 38143852 Free PMC article.
Adherence of health workers to guidelines for screening and management of cryptococcal meningitis in Uganda.
Namuju OC, Namuwenge PM, Kwizera R, Obuya E, Kirumira P, Naluyima R, Ahimbisibwe C, Ndyetukira J, Nakato H, Kirungi R, Gakuru J, Junju S, Nuwagira E, Rutakagirwa M, Nsibirwa S, Nabitaka V, Nalintya E, Mpoza E, Muzoora CK, Musubire AK, Boulware DR, Meya DB. Namuju OC, et al. Among authors: ahimbisibwe c. PLoS One. 2023 Apr 10;18(4):e0284165. doi: 10.1371/journal.pone.0284165. eCollection 2023. PLoS One. 2023. PMID: 37036886 Free PMC article.
Association of Hyponatremia on Mortality in Cryptococcal Meningitis: A Prospective Cohort.
Tugume L, Fieberg A, Ssebambulidde K, Nuwagira E, Williams DA, Mpoza E, Rutakingirwa MK, Kagimu E, Kasibante J, Nsangi L, Jjunju S, Musubire AK, Muzoora C, Lawrence DS, Rhein J, Meya DB, Hullsiek KH, Boulware DR, Abassi M; Adjunctive Sertraline for HIV-Associated Cryptococcal Meningitis (ASTRO-CM) Team. Tugume L, et al. Open Forum Infect Dis. 2022 Jun 17;9(7):ofac301. doi: 10.1093/ofid/ofac301. eCollection 2022 Jul. Open Forum Infect Dis. 2022. PMID: 35891691 Free PMC article.
Adjunctive sertraline for HIV-associated cryptococcal meningitis: a randomised, placebo-controlled, double-blind phase 3 trial.
Rhein J, Huppler Hullsiek K, Tugume L, Nuwagira E, Mpoza E, Evans EE, Kiggundu R, Pastick KA, Ssebambulidde K, Akampurira A, Williams DA, Bangdiwala AS, Abassi M, Musubire AK, Nicol MR, Muzoora C, Meya DB, Boulware DR; ASTRO-CM team. Rhein J, et al. Lancet Infect Dis. 2019 Aug;19(8):843-851. doi: 10.1016/S1473-3099(19)30127-6. Lancet Infect Dis. 2019. PMID: 31345462 Free PMC article. Clinical Trial.
Timing of antiretroviral therapy after diagnosis of cryptococcal meningitis.
Boulware DR, Meya DB, Muzoora C, Rolfes MA, Huppler Hullsiek K, Musubire A, Taseera K, Nabeta HW, Schutz C, Williams DA, Rajasingham R, Rhein J, Thienemann F, Lo MW, Nielsen K, Bergemann TL, Kambugu A, Manabe YC, Janoff EN, Bohjanen PR, Meintjes G; COAT Trial Team. Boulware DR, et al. N Engl J Med. 2014 Jun 26;370(26):2487-98. doi: 10.1056/NEJMoa1312884. N Engl J Med. 2014. PMID: 24963568 Free PMC article. Clinical Trial.
Detrimental Outcomes of Unmasking Cryptococcal Meningitis With Recent ART Initiation.
Rhein J, Hullsiek KH, Evans EE, Tugume L, Nuwagira E, Ssebambulidde K, Kiggundu R, Mpoza E, Musubire AK, Bangdiwala AS, Bahr NC, Williams DA, Abassi M, Muzoora C, Meya DB, Boulware DR; ASTRO-CM study team. Rhein J, et al. Open Forum Infect Dis. 2018 May 24;5(8):ofy122. doi: 10.1093/ofid/ofy122. eCollection 2018 Aug. Open Forum Infect Dis. 2018. PMID: 30094292 Free PMC article.
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