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Manipulating the 3D organization of the largest synthetic yeast chromosome.
Zhang W, Lazar-Stefanita L, Yamashita H, Shen MJ, Mitchell LA, Kurasawa H, Lobzaev E, Fanfani V, Haase MAB, Sun X, Jiang Q, Goldberg GW, Ichikawa DM, Lauer SL, McCulloch LH, Easo N, Lin SJ, Camellato BR, Zhu Y, Cai J, Xu Z, Zhao Y, Sacasa M; Build-A-Genome Class; Noyes MB, Bader JS, Deutsch S, Stracquadanio G, Aizawa Y, Dai J, Boeke JD. Zhang W, et al. Mol Cell. 2023 Dec 7;83(23):4424-4437.e5. doi: 10.1016/j.molcel.2023.10.015. Epub 2023 Nov 8. Mol Cell. 2023. PMID: 37944526 Free article.
Efficient synthesis for each of the eight stereoisomers of the iminosugars lentiginosine and 1,4-dideoxy-1,4-imino-D-arabinitol (DAB).
Liotta LJ, Antoine J, Brammer Basta LA, Campbell AS, Cole GY, Demick Brazile KA, Dogal Gardner NM, Fitzgerald ME, Francois JEK, French BM, Garafola SL, Giannetti CA, Granatosky EA, Harney AM, Hummel JT, Joyce AP, Keylor MH, Khubchandani JA, Korzeniecki C, Lieberman DC, Litterio JM, Maiorano MO, Marshall JF, McCarthy KA, Mendes Vieira A, Miller RM, Morrison ER, Moura SP, Neumann DF, Oliveira AF, Pace NJ, Plouffe JX, Pomfret MN, Reardon KN, Sheller-Miller SM, Smith MJ, Sullivan JL, Sweeney SW, Tougas KL. Liotta LJ, et al. Among authors: brammer basta la. Carbohydr Res. 2024 Nov;545:109280. doi: 10.1016/j.carres.2024.109280. Epub 2024 Sep 19. Carbohydr Res. 2024. PMID: 39326205
Atypically Modified Carbapenem Antibiotics Display Improved Antimycobacterial Activity in the Absence of β-Lactamase Inhibitors.
Gupta R, Al-Kharji NMSA, Alqurafi MA, Nguyen TQ, Chai W, Quan P, Malhotra R, Simcox BS, Mortimer P, Brammer Basta LA, Rohde KH, Buynak JD. Gupta R, et al. Among authors: brammer basta la. ACS Infect Dis. 2021 Aug 13;7(8):2425-2436. doi: 10.1021/acsinfecdis.1c00185. Epub 2021 Jun 30. ACS Infect Dis. 2021. PMID: 34191496 Free PMC article.